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  1. 原著論文

Simulation Study of Comparative Dosimetric Analysis of Coplanar Horizontal-Port Scanned Carbon-Ion Beam Therapy in the Head and Neck

https://repo.qst.go.jp/records/2000674
https://repo.qst.go.jp/records/2000674
646f9011-0760-4d15-910c-396161fe7b60
アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2024-09-06
タイトル
タイトル Simulation Study of Comparative Dosimetric Analysis of Coplanar Horizontal-Port Scanned Carbon-Ion Beam Therapy in the Head and Neck
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Daniel Ebner

× Daniel Ebner

Daniel Ebner

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Koto Masashi

× Koto Masashi

Koto Masashi

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Furuichi Wataru

× Furuichi Wataru

Furuichi Wataru

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Mori Shinichiro

× Mori Shinichiro

Mori Shinichiro

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抄録
内容記述タイプ Abstract
内容記述 Objective: Carbon-ion radiotherapy (CIRT) has demonstrated success in treating radioresistant disease within the head and neck, owing to its unique physical and radiobiological properties. Construction cost remains prohibitive; a center offering only a horizontal port may bridge this difficulty, but removal of the vertical port may prohibit treatment of disease near critical OARs. Building a center only containing a horizontal treatment port has been proposed as one method for cost savings.

Methods: Twenty complex cases of head and neck cancer previously treated with conventional CIRT were retrospectively planned using horizontal-port-only treatment incorporating noncoplanar treatment angles to achieve greater degrees of freedom. These were dosimetrically compared with the previous plans.

Results: Comparable D95 coverage of both PTV and GTV with ability to meet OAR constraints were feasible with horizontal-port-only treatment. Collectively differences were noted in PTV D95, brain stem Dmax, contralateral eye Dmax and V10 Gy(RBE); further qualitative differences were noted on a plan-by-plan basis dependent on disease location.

Conclusions: Horizontal-port-only treatment employing noncoplanar angles was feasible for complicated head and neck disease typically treated with CIRT, though careful consideration is necessary on a plan-by-plan basis.

Advances in knowledge: It is worth noting that noncoplanar approaches are not typically used with the current treatment gantry and may extend further the difference between horizontal port planning and a gantry-based gold standard.
書誌情報 The British Journal of Radiology

巻 96, 号 1149, p. 20221138, 発行日 2023-07
出版者
出版者 Oxford University Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 1748-880X
DOI
識別子タイプ DOI
関連識別子 10.1259/bjr.20221138
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