| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-01-26 |
| タイトル |
|
|
タイトル |
MRI Contrasting Agent Based on Mn-MOF-74 Nanoparticles with Coordinatively Unsaturated Sites. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Nobuhiko Iki
Ryuta Nakane
Atsuko Masuya-Suzuki
Yoshikazu Ozawa
Takako Maruoka
Megumi Iiyama
Akira Sumiyoshi
Ichio Aoki
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The development of magnetic resonance imaging (MRI) contrasting agents (CAs) that are safer and have a higher relaxivity than Gd(III)-based agents is a significant research topic. Herein, we propose the use of a Mn-based metal organic framework (MOF), Mn-MOF-74, characterized by a safe paramagnetic center, a coordinatively unsaturated site (CUS) for aquation, and a long rotational correlation time, endowing high relaxivity. Furthermore, biocompatibility and delivery to the tumor are generally expected for MOFs that are obtainable in the nanometer size range. |
| 書誌情報 |
Molecular imaging and biology
巻 25,
p. 968,
発行日 2023-01
|
| 出版者 |
|
|
出版者 |
Springer |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1860-2002 |
| PubMed番号 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
36653627 |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s11307-023-01801-0 |
