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アイテム
Carbon ion radiotherapy in the management of non-small cell lung cancer
https://repo.qst.go.jp/records/2000247
https://repo.qst.go.jp/records/200024794b94c0c-99e6-4ae7-97a7-5b9ff474397c
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||||||||||||
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| 公開日 | 2023-05-29 | |||||||||||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||||||||||
| タイトル | Carbon ion radiotherapy in the management of non-small cell lung cancer | |||||||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||||||||
| 言語 | ||||||||||||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||||||||
| 著者 |
Danushka Seneviratne
× Danushka Seneviratne
× Ishikawa Hitoshi
× Jingfang Mao
× Jingjing M. Dougherty
× Aaron Bush
× Mathew Thomas
× Rami Manochakian
× Yanyan Lou
× Dawn Owen
× Terence T. Sio
× Jessica Kirwan
× Stephen J. Ko
× Bradford S. Hoppe
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| 抄録 | ||||||||||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||||||||||
| 内容記述 | Despite advancements in local-regional and systemic therapies, non-small cell cancer (NSCLC) remains a leading cause of death worldwide. Among those treated with standard-of-care modalities, 30?60% experience disease recurrence. Carbon ion radiotherapy (CIRT) is a form of densely ionizing radiotherapy with unique physical and biological advantages over traditional photon and proton modalities. CIRT is expected to have a superior biological impact on tumors, and is believed to be less impacted by the presence of tumor hypoxia or cell cycle state. It also shows highly conformal physical dose deposition due to reduced lateral scattering of the particles, limiting the radiation dose delivered to adjacent organs at risk. To implement CIRT as a viable option in the treatment of NSCLC, technical aspects of treatment delivery ? including appropriate beam arrangements, dose calculation algorithms, radiobiological models, and methods of motion management ? must be thoroughly investigated. Furthermore, randomized clinical trials comparing CIRT versus traditional radiation modalities must be performed to show the benefits and risks associated with this novel treatment modality. This review discusses the rationale for utilizing CIRT in NSCLC, available clinical data to date, and the potential for future investigations that may pave the path for improving outcomes in those diagnosed with NSCLC. |
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| 書誌情報 |
Precision Radiation Oncology 巻 6, 号 1, p. 69-74, 発行日 2022-11 |
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| 出版者 | WILEY | |||||||||||||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||||||||
| 収録物識別子 | 2398-7324 | |||||||||||||||||||||||||||||||
| DOI | ||||||||||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||||||||||
| 関連識別子 | 10.1002/pro6.1146 | |||||||||||||||||||||||||||||||
