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Dose Estimation Model for Weakly Penetrating Radiation in Radionuclide Radiotherapy

https://repo.qst.go.jp/records/74920
https://repo.qst.go.jp/records/74920
ed846c35-c946-4e29-9750-7e5b59c9e0a3
Item type 会議発表用資料 / Presentation(1)
公開日 2019-03-22
タイトル
タイトル Dose Estimation Model for Weakly Penetrating Radiation in Radionuclide Radiotherapy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 赤羽, 恵一

× 赤羽, 恵一

WEKO 740446

赤羽, 恵一

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Akahane, Keiichi

× Akahane, Keiichi

WEKO 740447

en Akahane, Keiichi

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抄録
内容記述タイプ Abstract
内容記述 Purpose: In radionuclide therapy, beta and alpha particle emitters have been used as weakly penetrating radiation sources. However, the conventional dose calculation method for photons would not always be suitable for radionuclide therapy due to the short range in the body. The purpose of this study is to make a model of dose estimations for weakly penetrating radiation in radionuclide radiotherapy.

Methods: The issues of dose estimations to be considered in radionuclide therapy are the heterogeneously distributed doses and the higher dose levels for the possibility of not only stochastic but also deterministic effects. The former depends on the local concentrations of radionuclide with high radioactivity, and the latter is related to the physical and protection quantities with respect to radiation and tissue weighting factors. The dose distributions are determined based on the diagnostic images, and the exposed volumes are considered in each dose levels.

Results: The absorbed fractions from the source to target organs can be calculated considering the volumes as the sources in which the radionuclide concentrated. The wide range dose gradient in one organ requires the reconsideration of the concept of averaged absorbed dose, radiation and tissue weighting factors. The model estimates the internal doses in radionuclide therapy considering both stochastic and deterministic effects. This method can be applied for other radiotherapy and interventional radiology.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 The 18th Asia-Oceania Congress of Medical Physics (AOCMP) and the 16th South-East Asia Congress of Medical Physics (SEACOMP)
発表年月日
日付 2018-11-12
日付タイプ Issued
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