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重粒子線によるDNA損傷形態に関する研究
https://repo.qst.go.jp/records/72764
https://repo.qst.go.jp/records/727645efcd6a8-86e8-44e0-bf23-8e784f784708
Item type | 会議発表用資料 / Presentation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2018-04-27 | |||||
タイトル | ||||||
タイトル | 重粒子線によるDNA損傷形態に関する研究 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
赤松, 憲
× 赤松, 憲× 鹿園, 直哉× 藤本, 浩文× 平山, 亮一× 小池, 学× 赤松 憲× 鹿園 直哉× 藤本 浩文× 平山 亮一× 小池 学 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Clustered damage site, that is a DNA region with multiple lesions within a few helical turns, is believed to hardly be repaired. However, chemical and spatial details of them are not known. We have developed a method-ology for estimating localization of AP sites using Förster resonance energy transfer (FRET). We have already found that carbon ion can produce clustered DNA dam-age regions within a track using dry DNA film as an irra-diation sample by the FRET methodology. We applied the methodology to a cell-mimetic buffered DNA solu-tion irradiated with carbon ion beam with LET of ~90 keV/micron As a result, we found that the carbon ion tends to produce more clustered AP sites compared with 60Co gamma-rays. | |||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | H28年度HIMAC共同利用研究成果発表会 | |||||
発表年月日 | ||||||
日付 | 2017-04-18 | |||||
日付タイプ | Issued |