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Multimodal Thermo-Sensitive Polymer-Modified Liposome for Visualization and Treatment of Disseminated Cancer
https://repo.qst.go.jp/records/69743
https://repo.qst.go.jp/records/69743690cc3e8-7fd0-41a9-87c8-71d5ad8a9cae
Item type | 会議発表用資料 / Presentation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2009-04-27 | |||||
タイトル | ||||||
タイトル | Multimodal Thermo-Sensitive Polymer-Modified Liposome for Visualization and Treatment of Disseminated Cancer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kokuryo, Daisuke
× Kokuryo, Daisuke× et.al× 國領 大介 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A drug delivery system using a multimodal thermo-sensitive 'polymer-modified' liposome (MTPL) would be a powerful imaging tool to help avoid the side-effects of chemotherapy on the intact organ. In this study, an accumulation of and thermo-triggered drug release from MTPL were evaluated for disseminated-cancer using MRI and optical imaging. In the ex vivo optical images, the MTPL accumulation in the tumor area increased over 8 hours after the administration. In the T1-weighted MRI, the signal intensities in the bowel and the kidney changed after thermo-triggering. | |||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | ISMRM 17th Scientific Meeting & Exhibition | |||||
発表年月日 | ||||||
日付 | 2009-04-24 | |||||
日付タイプ | Issued |