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Usefulness of Methionine PET for predicting prognosis of patient with adenoc arcinoma in head and neck treated by carbon ion radiotherapy
https://repo.qst.go.jp/records/69130
https://repo.qst.go.jp/records/6913021998959-13ab-479e-afd6-1b072236abc3
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-10-15 | |||||
| タイトル | ||||||
| タイトル | Usefulness of Methionine PET for predicting prognosis of patient with adenoc arcinoma in head and neck treated by carbon ion radiotherapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Hasebe, Mitsuhiko
× Hasebe, Mitsuhiko× Yoshikawa, Kyosan× Ishikawa, Hiroyuki× Sagou, Kenji× Kawaguchi, Koji× Seto, Kanichi× 長谷部 充彦× 吉川 京燦× 石川 博之× 佐合 賢治 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | PURPOSE:C-11 methionine is a tracer for PET that can be used to assess metabolism of amino acid in tumor cells. The purpose of this study is to assess the ability of C-11 methionine PET (MET-PET) to predict prognosis of patient with adenocarcinoma in head and neck treated by carbon ion radiotherapy (CIRT). METHOD AND MATERIALS:We studied consecutive 23 patients with proven adenocarcinoma in head and neck who had been referred to our hospital for CIRT. 15 patients were male and 8 patients were female. The average patient age was 61.9 years (range 40 to 82). Patients were followed for 5.1 to 89.8 months (mean: 31.9 months) after CIRT. We evaluated the lesion semi-quantitatively on the basis of the Tumor-to-Normal-tissue Ratio (TNR). We statistically analyzed the relationship between tumor MET uptake level at pre and post CIRT, recurrence or metastasis rate, and patient prognosis using Kaplan-Meier analysis method. RESULTS:There were significant relationships between the level of tumor activity before CIRT and patients prognosis, recurrence and metastasis rate (p=0.029, 0.043, and 0.014) from Kaplan-Meier analysis. The level of tumor activity after CIRT also significantly related to patients prognosis, recurrence and metastasis rate (p=0.049, 0.043, and 0.014). No statistically significant relationship was observed between tumor uptake change after CIRT and survival rate. CONCLUSIONS:MET-PET is useful to predict patients survival rate, recurrence and metastasis rate in patients with head and neck adenocarcinoma treated by CIRT. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 89th AAOMS Annual Meeting, Scientific Sessions and Exhibition in conjunction with the Japanese Society of Oral and Maxillofacial Surgeons and the Korean Association of Oral and Maxillofacial Surgeons | |||||
| 発表年月日 | ||||||
| 日付 | 2007-10-13 | |||||
| 日付タイプ | Issued | |||||
