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アイテム
Evaluating Glycogen Signal Contamination in Muscle at 13C-MRS of the Liver
https://repo.qst.go.jp/records/68636
https://repo.qst.go.jp/records/68636d5b068a1-044b-4867-aac9-d2f2ee8e58f6
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-09-07 | |||||
| タイトル | ||||||
| タイトル | Evaluating Glycogen Signal Contamination in Muscle at 13C-MRS of the Liver | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tomiyasu, Moyoko
× Tomiyasu, Moyoko× Obata, Takayuki× Nishi, Yukio× Nakamoto, Hiromitsu× Tamura, Mitsuru× Nonaka, Hiroi× Ikehira, Hiroo× Kanno, Iwao× 富安 もよこ× 小畠 隆行× 西 幸雄× 中本 泰充× 田村 充× 野中 博意× 池平 博夫× 菅野 巖 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To evaluate the contamination of glycogen signal in muscle by that in the liver, the long-term monitoring over six hours of in vivo [1-13C] glycogen storage/degradation in the human liver and the left shoulder was achieved using a 3T GE Healthcare clinical MR system equipped with a homemade surface coil (34x35cm2). 13C MR spectra without localization were obtained from two healthy volunteers (1 male 22-old, 1 female 20-old) after oral administration of D-glucose of 85 g, included 99 % [1-13C] glucose of 10 g. A 99% [2-13C] acetone vial of 1 g was used as an external reference. Figure 1 shows the time course [1-13C] glycogen signal area intensities averaged of two volunteers in the liver and the shoulder. Each raw signal was normalized by that of the acetone before averaging. The maximum signal intensity in the liver was about four hours after the administration. At that time, the signal intensity in the shoulder was about one-fifth compared to that in the liver. Although the signal in the shoulder was resulted in [1-13C] glycogen synthesis in the muscle, the signal contribution from the muscle cannot be negligible in the case of the measurement of the liver by a surface coil without localization pulse sequence. Further investigation should allow a quantification analysis of the glycogen storage/degradation in the liver and the muscle and show a characteristic of glucose metabolism glucose, and provide a detailed diagnosis for hepatic function. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The fifth annual meeting of the society for molecalar imaging | |||||
| 発表年月日 | ||||||
| 日付 | 2006-09-02 | |||||
| 日付タイプ | Issued | |||||
