@misc{oai:repo.qst.go.jp:00068636,
 author = {Tomiyasu, Moyoko and Obata, Takayuki and Nishi, Yukio and Nakamoto, Hiromitsu and Tamura, Mitsuru and Nonaka, Hiroi and Ikehira, Hiroo and Kanno, Iwao and 富安 もよこ and 小畠 隆行 and 西 幸雄 and 中本 泰充 and 田村 充 and 野中 博意 and 池平 博夫 and 菅野 巖},
 month = {Sep},
 note = {To evaluate the contamination of glycogen signal in muscle by that in the liver, the long-term monitoring over six hours of in vivo [1-13C] glycogen storage/degradation in the human liver and the left shoulder was achieved using a 3T GE Healthcare clinical MR system equipped with a homemade surface coil (34x35cm2). 13C MR spectra without localization were obtained from two healthy volunteers (1 male 22-old, 1 female
20-old) after oral administration of D-glucose of 85 g, included 99 % [1-13C] glucose of 10 g. A 99% [2-13C] acetone vial of 1 g was used as an external reference. Figure 1 shows the time course [1-13C] glycogen signal area intensities averaged of two volunteers in the liver and the shoulder. Each raw signal was normalized by that of the
acetone before averaging. The maximum signal intensity in the liver was about four hours after the administration. At that time, the signal intensity in the shoulder was about one-fifth compared to that in the liver. Although the signal in the shoulder was resulted in [1-13C] glycogen synthesis in the muscle, the signal contribution from the muscle cannot be negligible in the case of the measurement of the liver by a surface coil without localization pulse sequence. Further investigation should allow a quantification analysis of the glycogen storage/degradation in the liver and the muscle and show a characteristic of glucose metabolism glucose, and provide a detailed diagnosis for hepatic function., The fifth annual meeting of the society for molecalar imaging},
 title = {Evaluating Glycogen Signal Contamination in Muscle at 13C-MRS of the Liver},
 year = {2006}
}