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重粒子線治療における肺癌腫瘍の至適分割法の研究:低酸素下加速分裂細胞の放射線感受性と血管誘導および低酸素関連遺伝子発現について
https://repo.qst.go.jp/records/60991
https://repo.qst.go.jp/records/60991f56665f1-efe8-421b-92a4-11c2a0969864
Item type | 会議発表用資料 / Presentation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2005-06-30 | |||||
タイトル | ||||||
タイトル | 重粒子線治療における肺癌腫瘍の至適分割法の研究:低酸素下加速分裂細胞の放射線感受性と血管誘導および低酸素関連遺伝子発現について | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
宮本, 忠昭
× 宮本, 忠昭× 石井, 幸子× 小藤, 昌志× 今井, 礼子× 古野, 亜紀× 三枝, 公美子× 今井, 高志× 宮本 忠昭× 石井 幸子× 小藤 昌志× 今井 礼子× 古野 亜紀× 三枝 公美子× 今井 高志 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Using cultured and nude mouse tumor cell (IA) derived frome a human lung cancer, we studied their radiosensitivity by focusing attention on the dynamics of tumor clonogens. The movement of clonogens in the regrowing IA tumor after X rays irradiation can be divided into three phases: first,: the early and rapid survival recovery(PLD repair) phase, second, the delay phase involving a certain lag in survival change, and third, the repopulation phase consisting of two stagea. Now we compare with the dynamics of tumor clonogens before or after exposure to X rays and carbon-ion beams. PLD repair was not observed in a carbon-ion beam. In relation to radiosensitivity and repair mechanism, we studied the gene expression of the cultured cell and nude tumor with a microarray method using 22K custom oligoallele. | |||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 重粒子線がん治療装置等共同利用研究成果発表会 | |||||
発表年月日 | ||||||
日付 | 2005-04-05 | |||||
日付タイプ | Issued |