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Automated image analysis for diameters and branching points of cerebral penetrating arteries and veins captured with two-photon microscopy.
https://repo.qst.go.jp/records/46989
https://repo.qst.go.jp/records/46989107bad9b-08b1-4807-920b-28230326d73a
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-12-16 | |||||
タイトル | ||||||
タイトル | Automated image analysis for diameters and branching points of cerebral penetrating arteries and veins captured with two-photon microscopy. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Sugashi, Takuma
× Sugashi, Takuma× Yoshihara, Kouichi× Kawaguchi, Hiroshi× Takuwa, Hiroyuki× Ito, Hiroshi× Kanno, Iwao× Yamada, Yukio× Masamoto, Kazuto× 須貸 拓馬× 吉原 光一× 川口 拓之× 田桑 弘之× 伊藤 浩× 菅野 巖× 正本 和人 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The present study was aimed to characterize 3-dimensional (3D) morphology of the cortical microvasculature (e.g., penetrating artery and emerging vein), using two-photon microscopy and automated analysis for their cross-sectional diameters and branching positions in the mouse cortex. We observed that both artery and vein had variable cross-sectional diameters across cortical depths. The mean diameter was similar for both artery (17 ± 5 μm) and vein (15 ± 5 μm), and there were no detectable differences over depths of 50-400 μm. On the other hand, the number of branches was slightly increased up to 400-μm depth for both the artery and vein. The mean number of branches per 0.1 mm vessel length was 1.7 ± 1.2 and 3.8 ± 1.6 for the artery and vein, respectively. This method allows for quantification of the large volume data of microvascular images captured with two-photon microscopy. This will contribute to the morphometric analysis of the cortical microvasculature in functioning brains. | |||||
書誌情報 |
Advances in experimental medicine and biology 巻 812, p. 209-215, 発行日 2014-04 |
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出版者 | ||||||
出版者 | Kluwer Academic/Plenum Publishers | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0065-2598 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 24729235 |