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Effects of a Diuretic and Its Combination with Chelating Agent on the Removal of Depleted Uranium in Rats
https://repo.qst.go.jp/records/45405
https://repo.qst.go.jp/records/454053983029a-dd4a-4306-bcca-f458f85d1ceb
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-01-28 | |||||
| タイトル | ||||||
| タイトル | Effects of a Diuretic and Its Combination with Chelating Agent on the Removal of Depleted Uranium in Rats | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ikeda, Mizuyo
× Ikeda, Mizuyo× Fukuda, Satoshi× Nakamura, Mariko× Yoshida, Hiroki× Yan, Xueming× Xie, Yuyuan× 池田 瑞代× 福田 俊× 中村 麻利子× 吉田 浩樹 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We examined the effects of a diuretic, isotonic saline, and chelating agent, catechol-3, 6-bis (methyleiminodiacetic acid) (CBMIDA), on the excretion and prevention of renal damage of depleted uranium (DU). Male Wistar rats (8 weeks old) divided into seven groups were preinjected intraperitoneally with 4 mg/kg DU and then the six groups were injected intraperitoneally with a diuretic, a diuretic plus isotonic saline, 480 mg/kg or 720 mg/kg CBMIDA alone, or 480 mg/kg or 720 mg/kg CBMIDA plus a diuretic and saline for three days, and the one group was as the control (no treatment). The rats were killed 6 days after DU injection. The results indicated that the diuretic alone and the diuretic with isotonic saline were not effective in removing uranium from the body and protecting the renal function, and also did not help to increase significantly the effects of CBMIDA. | |||||
| 書誌情報 |
Japanese Journal of Health Physics 巻 43, 号 4, p. 354-358, 発行日 2008-12 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0367-6110 | |||||
