WEKO3
アイテム
{"_buckets": {"deposit": "79b42d65-f4e7-4804-9a61-9d4cdac9dc30"}, "_deposit": {"created_by": 1, "id": "44794", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "44794"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00044794", "sets": ["1"]}, "author_link": ["444784", "444783", "444785", "444782"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "18", "bibliographicPageStart": "13", "bibliographicVolumeNumber": "50", "bibliographic_titles": [{"bibliographic_title": "Journal of Labelled Compounds \u0026 Radiopharmaceuticals"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We evaluated lipophilicity and biodistribution of a series of 99mTc(CO)3-ether isonitrile complexes to\ndetermine whether different lipophilicity and structure of isonitrile ligands would improve the imaging properties of\nthe radiopharmaceutical for the heart. Novel 99mTc(CO)3-MIBI analogs were prepared and analyzed by radio-HPLC,\nand their lipophilicity was determined. These new complexes could be bi- or tri-substituted in specified pH\nconditions like 99mTc(CO)3-MIBI. These new complexes exhibited low liver, lungs and blood uptake compared with\n[99mTc(CO)3(MIBI)3]+ though their heart uptake was not so high. Among these complexes, [99mTc(CO)3(EPI)2(OH2)]+\nshowed higher target to non-target ratios at 5 and 30 min post-injection than that of [99mTc(CO)3(MIBI)3]+. Copyright\n# 2007 John Wiley \u0026 Sons, Ltd", "subitem_description_type": "Abstract"}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0362-4803", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hao, Guiyang"}], "nameIdentifiers": [{"nameIdentifier": "444782", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "JIANYING, ZANG"}], "nameIdentifiers": [{"nameIdentifier": "444783", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "BOLI, LIU"}], "nameIdentifiers": [{"nameIdentifier": "444784", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hao Guiyang", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "444785", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Preparation and biodistribution of novel 99mTc(CO)3-CNR complexes for myocardial imaging", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Preparation and biodistribution of novel 99mTc(CO)3-CNR complexes for myocardial imaging"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/44794", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-02-19"}, "publish_date": "2007-02-19", "publish_status": "0", "recid": "44794", "relation": {}, "relation_version_is_last": true, "title": ["Preparation and biodistribution of novel 99mTc(CO)3-CNR complexes for myocardial imaging"], "weko_shared_id": -1}
Preparation and biodistribution of novel 99mTc(CO)3-CNR complexes for myocardial imaging
https://repo.qst.go.jp/records/44794
https://repo.qst.go.jp/records/44794971c8d84-bbfd-4cf8-9fc1-7c850893adfc
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-02-19 | |||||
タイトル | ||||||
タイトル | Preparation and biodistribution of novel 99mTc(CO)3-CNR complexes for myocardial imaging | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hao, Guiyang
× Hao, Guiyang× JIANYING, ZANG× BOLI, LIU× Hao Guiyang |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We evaluated lipophilicity and biodistribution of a series of 99mTc(CO)3-ether isonitrile complexes to determine whether different lipophilicity and structure of isonitrile ligands would improve the imaging properties of the radiopharmaceutical for the heart. Novel 99mTc(CO)3-MIBI analogs were prepared and analyzed by radio-HPLC, and their lipophilicity was determined. These new complexes could be bi- or tri-substituted in specified pH conditions like 99mTc(CO)3-MIBI. These new complexes exhibited low liver, lungs and blood uptake compared with [99mTc(CO)3(MIBI)3]+ though their heart uptake was not so high. Among these complexes, [99mTc(CO)3(EPI)2(OH2)]+ showed higher target to non-target ratios at 5 and 30 min post-injection than that of [99mTc(CO)3(MIBI)3]+. Copyright # 2007 John Wiley & Sons, Ltd |
|||||
書誌情報 |
Journal of Labelled Compounds & Radiopharmaceuticals 巻 50, 号 1, p. 13-18, 発行日 2007-01 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0362-4803 |