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Seizure frequency and bilateral temporal abnormalities: a proton magnetic resonance spectroscopy of temporal lobe epilepsy
https://repo.qst.go.jp/records/44012
https://repo.qst.go.jp/records/440127b01b958-72cb-404a-b54d-b725bcd05e35
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2006-03-15 | |||||
タイトル | ||||||
タイトル | Seizure frequency and bilateral temporal abnormalities: a proton magnetic resonance spectroscopy of temporal lobe epilepsy | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Yasuhiro, Someya
× Yasuhiro, Someya× Obata, Takayuki× Suhara, Tetsuya× Ota, Yoshihisa× Ikehira, Hiroo× Tanada, Shuji× Hirakawa, K× Okubo, Yoshiro× Sasaki, Yasuhito× 小畠 隆行× 須原 哲也× 池平 博夫× 棚田 修二× 大久保 善朗× 佐々木 康人 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Proton magnetic resonance spectroscopy ((1)H-MRS) was performed in seven healthy volunteers and 17 patients with temporal lobe epilepsy (TLE) to clarify the correlation of the severity of epilepsy with bilateral temporal changes in N-acetylaspartate (NAA), choline-containing compounds (Cho) and creatine + phosphocreatine (Cr). Despite unilateral EEG focus, bilateral temporal reduction in NAA /(Cho + Cr) was revealed in patients with intractable seizures. The potential for seizure generation correlated with the NAA /(Cho + Cr) reduction not only on the ipsilateral side but also on the contralateral side. Proton MRS proved to be a useful measurement for obtaining important information about the neuronal changes as well as the lateralization of the epileptogenic focus in TLE patients. Copyright 2000 BEA Trading Ltd. | |||||
書誌情報 |
Seizure 巻 9, 号 4, p. 274-279, 発行日 2000-06 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1059-1311 |