@article{oai:repo.qst.go.jp:00044012,
 author = {Yasuhiro, Someya and Obata, Takayuki and Suhara, Tetsuya and Ota, Yoshihisa and Ikehira, Hiroo and Tanada, Shuji and Hirakawa, K and Okubo, Yoshiro and Sasaki, Yasuhito and 小畠 隆行 and 須原 哲也 and 池平 博夫 and 棚田 修二 and 大久保 善朗 and 佐々木 康人},
 issue = {4},
 journal = {Seizure},
 month = {Jun},
 note = {Proton magnetic resonance spectroscopy ((1)H-MRS) was performed in seven healthy volunteers and 17 patients with temporal lobe epilepsy (TLE) to clarify the correlation of the severity of epilepsy with bilateral temporal changes in N-acetylaspartate (NAA), choline-containing compounds (Cho) and creatine + phosphocreatine (Cr). Despite unilateral EEG focus, bilateral temporal reduction in NAA /(Cho + Cr) was revealed in patients with intractable seizures. The potential for seizure generation correlated with the NAA /(Cho + Cr) reduction not only on the ipsilateral side but also on the contralateral side. Proton MRS proved to be a useful measurement for obtaining important information about the neuronal changes as well as the lateralization of the epileptogenic focus in TLE patients. Copyright 2000 BEA Trading Ltd.},
 pages = {274--279},
 title = {Seizure frequency and bilateral temporal abnormalities: a proton magnetic resonance spectroscopy of temporal lobe epilepsy},
 volume = {9},
 year = {2000}
}