{"created":"2023-05-15T15:03:49.218237+00:00","id":86373,"links":{},"metadata":{"_buckets":{"deposit":"90338f7b-a5a4-4ca9-8ce6-ae388f5860da"},"_deposit":{"created_by":1,"id":"86373","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"86373"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00086373","sets":["11"]},"author_link":["1053505","1053504"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-07","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"535","bibliographic_titles":[{"bibliographic_title":"NLだより"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"α線放出核種を用いた最新研究についての紹介。\n肝臓などに蓄積した遊離225Acの排出方法の開発を目的とし、様々なキレート剤のin vivoでの効果を比較し、実現の可能性を評価。またキレート剤の効果とその科学構造を比較することで、関連性を検討。\nCa-TTHAまたはCa-DTPAが遊離225Aｃの全身クリアランスに効果的であることが明確に。これらのキレート剤の投与は225Ａｃ標識薬から放出した遊離225Ａｃによって引き起こされる予期しない放射線被ばくを軽減し、225ＡｃＴＡＴの開発を促進するための新しい手法となる可能性がある。\n","subitem_description_type":"Abstract"}]},"item_10004_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長瀬ランダウア（株）"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"品田, 光洋"}],"nameIdentifiers":[{"nameIdentifier":"1053504","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mitsuhiro, Shinada","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1053505","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"225Ac治療薬剤開発に資する遊離225Ac除去法の基礎研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"225Ac治療薬剤開発に資する遊離225Ac除去法の基礎研究"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-06-22"},"publish_date":"2022-06-22","publish_status":"0","recid":"86373","relation_version_is_last":true,"title":["225Ac治療薬剤開発に資する遊離225Ac除去法の基礎研究"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T17:01:39.228551+00:00"}