{"created":"2023-05-15T15:03:46.298898+00:00","id":86321,"links":{},"metadata":{"_buckets":{"deposit":"17aa889e-e706-4d1d-bb2d-fbd70286846b"},"_deposit":{"created_by":1,"id":"86321","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"86321"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00086321","sets":["10:28"]},"author_link":["1052965","1052968","1052967","1052966"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2022-05-26","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"我々は以前の研究で酵母の転写開始点の+1ヌクレオソームのエントリーサイト(転写開始点側の末端)がAA/TT配列に富んでいることを示した。更に、酵母の+1ヌクレオソームを再構成し、AA/TT配列がMNaseによって切断されやすい性質があることを見出した。本研究では、この現象の分子メカニズムをより詳細に解明するために、AA/TT等の配列を有するヌクレオソームを複数作成し、DNA上の蛍光色素間の距離をFRET法で解析することで、AA/TT配列を有するヌクレオソームがヒストンタンパク質からよりほどけやすいことを明らかにした。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"量子生命科学会 第4回大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"角南, 智子"}],"nameIdentifiers":[{"nameIdentifier":"1052965","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河野, 秀俊"}],"nameIdentifiers":[{"nameIdentifier":"1052966","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomoko, Sunami","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1052967","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hidetoshi, Kono","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1052968","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"転写開始点のヌクレオソームDNAアンラッピングのFRET解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"転写開始点のヌクレオソームDNAアンラッピングのFRET解析"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-04-22"},"publish_date":"2022-04-22","publish_status":"0","recid":"86321","relation_version_is_last":true,"title":["転写開始点のヌクレオソームDNAアンラッピングのFRET解析"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T17:02:59.010188+00:00"}