{"created":"2023-05-15T15:03:40.662899+00:00","id":86226,"links":{},"metadata":{"_buckets":{"deposit":"ae8a90c3-ffe5-4473-96cc-202553587de8"},"_deposit":{"created_by":1,"id":"86226","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"86226"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00086226","sets":["10:28"]},"author_link":["1052198","1052200","1052201","1052202","1052203","1052204","1052199","1052205"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2022-05-26","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"PAC タンパク質は、光受容によって酵素反応を活性化する。その分子構造は既知であるが、(1) 光異性化過程の詳細、(2) 光受容ドメインと酵素ドメインのクロストーク機序は未解明である。そこで、光化学反応に駆動される動的な構造変化の解析に有効な QM/MM 分子シミュレーションを行った。その結果、光受容ドメインの光活性化による Trp90 のフリップ、および光受容ドメインから酵素ドメインに続く長い C 末ヘリックスの相対配置の変化が起こることが分かった。これらの変化とクロストークの関係を議論する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"量子生命科学会 第4回大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田口, 真彦"}],"nameIdentifiers":[{"nameIdentifier":"1052198","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"櫻庭, 俊"}],"nameIdentifiers":[{"nameIdentifier":"1052199","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"チャン, ワイ ソオン"}],"nameIdentifiers":[{"nameIdentifier":"1052200","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河野, 秀俊"}],"nameIdentifiers":[{"nameIdentifier":"1052201","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masahiko, Taguchi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1052202","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shun, Sakuraba","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1052203","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Soon Chan, Wai","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1052204","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hidetoshi, Kono","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1052205","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"QM/MM 分子シミュレーションによる光活性化酵素 PAC の機能解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"QM/MM 分子シミュレーションによる光活性化酵素 PAC の機能解析"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-04-25"},"publish_date":"2022-04-25","publish_status":"0","recid":"86226","relation_version_is_last":true,"title":["QM/MM 分子シミュレーションによる光活性化酵素 PAC の機能解析"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T17:05:01.219839+00:00"}