@article{oai:repo.qst.go.jp:00086196, author = {Masayuki, Fujinaga and Ohkubo, Takayuki and Tomoteru, Yamasaki and Katsushi, Kumata and Nobuki, Nengaki and Zhang, Ming-Rong and Masayuki, Fujinaga and Ohkubo, Takayuki and Tomoteru, Yamasaki and Katsushi, Kumata and Nobuki, Nengaki and Zhang, Ming-Rong}, journal = {Organic Letters}, month = {May}, note = {Scandium triflate-catalyzed N-[18F]fluoroalkylation of aryl- or heteroaryl-amines with [18F]epifluorohydrin ([18F]2) was investigated. This reaction is mild and provides one-step access to N-[18F]fluoroalkylated aryl- or heteroaryl-amines, which are used for positron emission tomography imaging. Use of 2,2,2-trifluoroethanol as a cosolvent improved the re-action efficiency. The use of (S)- or (R)-[18F]2 produced the corresponding enantiomeric N-[18F]fluoroalkylated anilines.}, pages = {4024--4028}, title = {Scandium triflate-catalyzed N-[18F]Fluoroalkylation of aryl- or heteroaryl-amines with [18F]epifluorohydrin under mild condi-tions}, volume = {24}, year = {2022} }