{"created":"2023-05-15T15:03:28.412308+00:00","id":85992,"links":{},"metadata":{"_buckets":{"deposit":"bd7a2b2e-e855-4242-9c6f-caabc83fe1a2"},"_deposit":{"created_by":1,"id":"85992","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"85992"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00085992","sets":["1"]},"author_link":["1041108","1041106","1041118","1041116","1041112","1041105","1041113","1041102","1041109","1041114","1041119","1041117","1041115","1041103","1041107","1041104","1041110","1041111","1041101"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-01","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{"bibliographic_title":"Cancer medicine"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: The goal of this multicenter retrospective study of patients with head and neck malignancies was to evaluate the efficacy and safety of carbon-ion (C-ion) radiotherapy (RT) after photon RT.\nMethods: We enrolled 56 patients with head and neck malignancies who underwent re-irradiation (re-RT) using C-ions between November 2003 and March 2019, treated previously with photon RT. The tumors at re-RT were located in the sinonasal cavities (n = 20, 35.7%), skull base (n = 12, 21.4%), and orbit (n = 7, 12.5%). The tumors at the initial RT were located in the sinonasal cavities (n = 13, 23.2%), skull base (n = 9, 16.1%), and orbit (n = 9, 16.1%). The median period between the initial RT and re-RT was 41 (4-568) months. The most common histology of re-RT was squamous cell carcinoma (n = 11, 19.6%). The most commonly used protocol was 57.6 Gy (relative biological effectiveness) in 16 fractions (n = 23, 41.1%). Surgery preceded re-RT in three patients (5.4%). One patient with malignant melanoma received concurrent chemotherapy.\nResults: The 2-year local control, progression-free survival, and overall survival rates were 66.5%, 36.9%, and 67.9%, respectively. The median follow-up time was 28 months. Two patients (3.6%) developed grade ≥ 3 acute toxicities, and 14 (25.0%) developed grade ≥ 3 late toxicities. A single patient had confirmed grade 5 dermatitis with infection.\nConclusion: Re-RT using C-ions for head and neck malignancies after photon RT is an effective treatment with tolerable toxicity.","subitem_description_type":"Abstract"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"35393701","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1002/cam4.4741","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2045-7634","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takahashi, Daiki"}],"nameIdentifiers":[{"nameIdentifier":"1041101","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Demizu, Yusuke"}],"nameIdentifiers":[{"nameIdentifier":"1041102","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koto, Masashi"}],"nameIdentifiers":[{"nameIdentifier":"1041103","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kubo, Nobuteru"}],"nameIdentifiers":[{"nameIdentifier":"1041104","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suefuji, Hiroaki"}],"nameIdentifiers":[{"nameIdentifier":"1041105","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikawa, Hiroaki"}],"nameIdentifiers":[{"nameIdentifier":"1041106","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohno, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"1041107","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shioyama, Yoshiyuki"}],"nameIdentifiers":[{"nameIdentifier":"1041108","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okimoto, Tomoaki"}],"nameIdentifiers":[{"nameIdentifier":"1041109","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"1041110","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Daiki, Takahashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041111","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masashi, Koto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041112","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nobuteru, Kubo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041113","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroaki, Suefuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041114","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroaki, Ikawa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041115","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuya, Ohno","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041116","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshiyuki, Shioyama","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041117","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomoaki, Okimoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041118","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroshi, Tsuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1041119","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Multicenter study of re-irradiation using carbon-ions for head and neck malignancies after photon radiotherapy.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Multicenter study of re-irradiation using carbon-ions for head and neck malignancies after photon radiotherapy."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-04-15"},"publish_date":"2022-04-15","publish_status":"0","recid":"85992","relation_version_is_last":true,"title":["Multicenter study of re-irradiation using carbon-ions for head and neck malignancies after photon radiotherapy."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T17:23:41.121821+00:00"}