{"created":"2023-05-15T15:03:25.710165+00:00","id":85930,"links":{},"metadata":{"_buckets":{"deposit":"490a37cd-e3e0-4452-b063-6b37b5856151"},"_deposit":{"created_by":1,"id":"85930","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"85930"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00085930","sets":["1"]},"author_link":["1040934","1040935","1040937","1040943","1040939","1040942","1040936","1040940","1040941","1040938"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"75","bibliographicVolumeNumber":"5","bibliographic_titles":[{"bibliographic_title":"Communications Physics"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Clock proteins maintain constant enzymatic activity regardless of temperature, even though thermal fluctuation is accelerated as temperature increases. We investigated temperature influences on the dynamics of KaiC, a temperature-compensated ATPase in the cyanobacterial circadian clock system, using quasielastic neutron scattering. The frequency of picosecond to sub-nanosecond incoherent local motions in KaiC was accelerated by a factor of only 1.2 by increasing the temperature by 10°C. This temperature insensitivity of the local motions was not necessarily unique to KaiC, but confirmed also for a series of temperature-sensitive mutants of KaiC and proteins other than clock-related proteins. Rather, the dynamics associated with the temperature-compensatory nature of the reaction- and system-level was found in global diffusional motions, which was suggested to regulate the temperature dependence of ATPase activity and dephosphorylation process presumably through changes in the hexamer conformation of KaiC. The spatiotemporal scale at which cross-scale causality of the temperature sensitivity is established is finite, and extends down to picosecond to sub-nanosecond dynamics only in a very limited part of KaiC, not in its entire part.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1038/s42005-022-00852-z","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://rdcu.be/cKDwg","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2399-3650","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Furuike, Yoshihiko"}],"nameIdentifiers":[{"nameIdentifier":"1040934","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ouyang, Dongyan"}],"nameIdentifiers":[{"nameIdentifier":"1040935","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tominaga, Taiki"}],"nameIdentifiers":[{"nameIdentifier":"1040936","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuhito, Matsuo"}],"nameIdentifiers":[{"nameIdentifier":"1040937","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mukaiyama, Atsushi"}],"nameIdentifiers":[{"nameIdentifier":"1040938","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawakita, Yukinobu"}],"nameIdentifiers":[{"nameIdentifier":"1040939","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoru, Fujiwara"}],"nameIdentifiers":[{"nameIdentifier":"1040940","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akiyama, Shuji"}],"nameIdentifiers":[{"nameIdentifier":"1040941","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuhito, Matsuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1040942","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoru, Fujiwara","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1040943","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Cross-scale Analysis of Temperature Compensation in the Cyanobacterial Circadian Clock System","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Cross-scale Analysis of Temperature Compensation in the Cyanobacterial Circadian Clock System"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-24"},"publish_date":"2022-02-24","publish_status":"0","recid":"85930","relation_version_is_last":true,"title":["Cross-scale Analysis of Temperature Compensation in the Cyanobacterial Circadian Clock System"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T17:24:14.227036+00:00"}