{"created":"2023-05-15T15:02:49.153200+00:00","id":85152,"links":{},"metadata":{"_buckets":{"deposit":"37eb1465-4f2e-4d11-bf5d-31e27f242b5b"},"_deposit":{"created_by":1,"id":"85152","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"85152"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00085152","sets":["1"]},"author_link":["1043525","1043526","1043528","1043536","1043527","1043520","1043532","1043545","1043540","1043530","1043531","1043519","1043542","1043544","1043538","1043524","1043541","1043534","1043533","1043529","1043537","1043543","1043523","1043521","1043522","1043539","1043535"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageStart":"e056424","bibliographicVolumeNumber":"12","bibliographic_titles":[{"bibliographic_title":"BMJ open"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Concurrent chemoradiotherapy is considered the standard treatment strategy for locally advanced cervical cancer. Most recent reports indicate that patients with bulky tumours or adenocarcinoma subtypes have poorer local control. Carbon-ion radiotherapy (CIRT) with the concurrent use of chemotherapy has shown promising results in such cases of difficult-to-treat uterine cervical cancer. Programmed death-ligand 1 (PD-L1) upregulation was observed in tumour tissue samples from patients who had undergone CIRT. Thus, a combination of CIRT and anti-PD-L1 antibody may suppress metastasis by activating antitumour immune response, in addition to exhibiting strong local 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