@article{oai:repo.qst.go.jp:00085010, author = {Yudi Utomo, Rohmad and Okada, Satoshi and Akira, Sumiyoshi and Asawa, Yasunobu and Seung Ban, Hyun and Yoshimori, Atsushi and Aoki, Ichio and Jürgen, Bajorath and Nakamura, Hiroyuki and Akira, Sumiyoshi and Ichio, Aoki}, journal = {RSC Advances}, month = {May}, note = {A curcumin derivative conjugated with Gd-DO3A (Gd-DO3A-Comp.B) was synthesised as an MRI contrast agent for detecting the amyloid- (A) fibrillation process. Gd-DO3A-Comp.B inhibited Aß aggregation significantly and detected the fibril growth at 20 uM of AB with 10 uM of probe concentration by T1-weighted MR imaging.}, pages = {5027--5030}, title = {Development of an MRI contrast agent for both detection and inhibition of the amyloid-b fibrillation process}, volume = {12}, year = {2022} }