{"created":"2023-05-15T15:02:41.489973+00:00","id":84998,"links":{},"metadata":{"_buckets":{"deposit":"2f7dbe2e-36ea-48a9-86f0-d49d31bf2c57"},"_deposit":{"created_by":1,"id":"84998","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"84998"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00084998","sets":["1"]},"author_link":["1042612","1042620","1042608","1042616","1042613","1042617","1042611","1042614","1042619","1042615","1042610","1042621","1042609","1042618"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-11","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"292","bibliographicPageStart":"285","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Annals of Nuclear Medicine"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose\nTo reduce postoperative complications, intraoperative lymph node (LN) diagnosis with 18F-fluoro-2-deoxy-D-glucose (FDG) is expected to optimize the extent of LN dissection, leading to less invasive surgery. However, such a diagnostic device has not yet been realized. We proposed the concept of coincidence detection wherein a pair of scintillation crystals formed the head of the forceps. To estimate the clinical impact of this detector, we determined the cut-off value using FDG as a marker for intraoperative LN diagnosis in patients with esophageal cancer, the specifications needed for the detector, and its feasibility using numerical simulation.\n\nMethods\nWe investigated the dataset including pathological diagnosis and radioactivity of 1073 LNs resected from 20 patients who underwent FDG-positron emission tomography followed by surgery for esophageal cancer on the same day. The specifications for the detector were determined assuming that it should measure 100 counts (less than 10% statistical error) or more within the intraoperative measurement time of 30 s. The detector sensitivity was estimated using GEANT4 simulation and the expected diagnostic ability was calculated.\n\nResults\nThe cut-off value was 620 Bq for intraoperative LN diagnosis. The simulation study showed that the detector had a radiation detection sensitivity of 0.96%, which was better than the estimated specification needed for the detector. Among the 1035 non-metastatic LNs, 815 were below the cut-off value.\n\nConclusion\nThe forceps-type coincidence detector can provide sufficient sensitivity for intraoperative LN diagnosis. Approximately 80% of the prophylactic LN dissections in esophageal cancer can be avoided using this detector.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s12149-021-01701-9","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s12149-021-01701-9","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-7187","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Miwako, Takahashi"}],"nameIdentifiers":[{"nameIdentifier":"1042608","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshimura, Shuntaro"}],"nameIdentifiers":[{"nameIdentifier":"1042609","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sodai, Takyu"}],"nameIdentifiers":[{"nameIdentifier":"1042610","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aikou, Susumu"}],"nameIdentifiers":[{"nameIdentifier":"1042611","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okumura, Yasuhiro"}],"nameIdentifiers":[{"nameIdentifier":"1042612","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yagi, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"1042613","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukayama, Masashi"}],"nameIdentifiers":[{"nameIdentifier":"1042614","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Momose, Toshimitsu"}],"nameIdentifiers":[{"nameIdentifier":"1042615","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Seto, Yasuyuki"}],"nameIdentifiers":[{"nameIdentifier":"1042616","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Taiga, Yamaya"}],"nameIdentifiers":[{"nameIdentifier":"1042617","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miwako, Takahashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1042618","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sodai, Takyu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1042619","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Seto, Yasuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1042620","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Taiga, Yamaya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1042621","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A design of forceps-type coincidence radiation detector for intraoperative LN diagnosis: clinical impact estimated from LNs data of 20 esophageal cancer patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A design of forceps-type coincidence radiation detector for intraoperative LN diagnosis: clinical impact estimated from LNs data of 20 esophageal cancer patients"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-08"},"publish_date":"2021-12-08","publish_status":"0","recid":"84998","relation_version_is_last":true,"title":["A design of forceps-type coincidence radiation detector for intraoperative LN diagnosis: clinical impact estimated from LNs data of 20 esophageal cancer patients"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T17:21:32.503189+00:00"}