@article{oai:repo.qst.go.jp:00084984,
 author = {Hiroaki, Ikawa and Masashi, Koto and Bhattacharyya, Tapesh and Takashi, Kaneko and Hirotoshi, Takiyama and Makoto, Shinoto and Akihiro, Nomoto and Shigeru, Yamada and Hiroshi, Tsuji and Hiroaki, Ikawa and Masashi, Koto and Bhattacharyya, Tapesh and Takashi, Kaneko and Hirotoshi, Takiyama and Makoto, Shinoto and Akihiro, Nomoto and Shigeru, Yamada and Hiroshi, Tsuji},
 journal = {Practical Radiation Oncology},
 month = {Feb},
 note = {We introduce the utility of iodine paste markers using endodontic materials for the accurate contouring of mucosal lesions of oral mucosal melanoma (OMM), which are difficult to delineate on imaging during the planning of carbon-ion radiation therapy (CIRT). The patient had a primary OMM located in the palatal mucosa without palatal or maxillary bone invasion. A dental root canal filling material, which is a calcium hydroxide/iodoform non-hardenable paste, was used as a marker. We first performed treatment planning computed tomography (CT) without an iodine paste marker for mucosal lesions. Subsequently, we placed an iodine paste marker on the palatal mucosal lesion to accurately delineate the mucosal lesions of the palate. Finally, we took reference CT with an iodine paste marker. CT without the marker was fused to the reference CT with markers during treatment planning, and the gross tumor volume (GTV) was contoured. Thereafter, CIRT was delivered without markers. During CIRT, expected acute mucositis was observed in the area of the planning target volume (PTV), including melanosis, in accordance with the dose distribution. The use of iodine paste markers for localized mucosal lesions, which are difficult to delineate on CT and MRI, may be useful for contouring GTVs on treatment planning CT accurately.},
 title = {Accurate delineation of mucosal lesions in treatment planning computed tomography using iodine paste markers for oral mucosal melanoma},
 year = {2022}
}