{"created":"2023-05-15T15:02:25.997221+00:00","id":84655,"links":{},"metadata":{"_buckets":{"deposit":"7ddc8e16-28a0-4075-b7cd-672595d3537a"},"_deposit":{"created_by":1,"id":"84655","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"84655"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00084655","sets":["1"]},"author_link":["1021720","1021715","1021714","1021716","1021717","1021719","1021718"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageStart":"1966","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Antioxidants"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Recently, increasing attention has been paid to the quantum mechanical behavior in biology. In this study, we have investigated the involvement of the quantum mechanical tunneling in the hydrogen-transfer reaction from Trolox, a water-soluble analog of vitamin E (α-tocopherol), to 2,2-diphenyl-1-picrylhydrazyl radical (DPPH•) by in a phosphate buffer solution (0.05 M, pH 7.0). DPPH• was used as a reactivity model of reactive oxygen species and solubilized in water by β-cyclodextrin (β-CD). The second-order rate constants, kH and kD, in 0.05 M phosphate buffer solutions prepared with H2O (pH 7.0) and D2O (pD 7.0), respectively, were determined for the reaction between Trolox and DPPH• by a stopped-flow technique at various temperatures (283–303 K). Large kinetic isotope effects (KIE, kH/kD) were observed for the hydrogen-transfer reaction from Trolox to the β-CD-solubilized DPPH• in the whole temperature range. The isotopic ratio of the Arrhenius prefactor (AH/AD = 0.003) as well as the isotopic difference in the activation energies (19 kJ mol–1) indicates that quantum mechanical tunneling plays a role in the reaction.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"34943069","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/antiox10121966","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.mdpi.com/2076-3921/10/12/1966","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2076-3921","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakanishi, Ikuo"}],"nameIdentifiers":[{"nameIdentifier":"1021714","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shoji, Yoshimi"}],"nameIdentifiers":[{"nameIdentifier":"1021715","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohkubo, Kei"}],"nameIdentifiers":[{"nameIdentifier":"1021716","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuzumi, Shunichi"}],"nameIdentifiers":[{"nameIdentifier":"1021717","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikuo, Nakanishi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1021718","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshimi, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1021719","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kei, Ohkubo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1021720","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Tunneling in the Hydrogen-Transfer Reaction from a Vitamin E Analog to an Inclusion Complex of 2,2-Diphenyl-1-picrylhydrazyl Radical with β-Cyclodextrin in an Aqueous Buffer Solutions at Ambient Temperature","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Tunneling in the Hydrogen-Transfer Reaction from a Vitamin E Analog to an Inclusion Complex of 2,2-Diphenyl-1-picrylhydrazyl Radical with β-Cyclodextrin in an Aqueous Buffer Solutions at Ambient Temperature"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-07"},"publish_date":"2021-12-07","publish_status":"0","recid":"84655","relation_version_is_last":true,"title":["Tunneling in the Hydrogen-Transfer Reaction from a Vitamin E Analog to an Inclusion Complex of 2,2-Diphenyl-1-picrylhydrazyl Radical with β-Cyclodextrin in an Aqueous Buffer Solutions at Ambient Temperature"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T18:17:11.799848+00:00"}