{"created":"2023-05-15T15:02:12.855025+00:00","id":84368,"links":{},"metadata":{"_buckets":{"deposit":"0b36bf9c-f67d-4a6c-baaf-cfe18eb23c55"},"_deposit":{"created_by":1,"id":"84368","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"84368"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00084368","sets":["10:28"]},"author_link":["1018938","1018937","1018942","1018943","1018933","1018934","1018941","1018936","1018939","1018932","1018935","1018940"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2021-12-19","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Resveratrol (1), 3,5,4'-trihydroxy-trans-stilbene, found in grapes is one of the representative antioxidants that shows a plethora of remarkable biological properties. On the other hand, pterostilbene (2), a methylated analog of 1, has attracted much attention due to its enhanced bioavailability as compared to that of 1. However, little is known about the radical-scavenging mechanism of 2. There are two mechanisms in the radical-scavenging reaction of phenolic antioxidants: a one-step hydrogen-atom transfer from the phenolic OH group; and an electron transfer followed by proton transfer. Redox inactive metal ions, such as magnesium ion (Mg2+), are a powerful tool to distinguish between these two mechanisms, because electron-transfer reactions are known to be accelerated by their presence. In fact, a significant acceleration in the radical-scavenging reaction of 1 was observed in the presence of Mg2+ in acetonitrile (MeCN), suggesting that the reaction may proceed via the electron-transfer mechanism (Chem. Lett. 2007, 36, 1276). We report herein the effect of Mg2+ on the scavenging reaction of galvinoxyl radical (GO) by 2 in MeCN. GO has been frequently used as a reactivity model of reactive oxygen radicals to estimate the activity of antioxidants.\nUpon mixing of 2 with GO on a UNISOKU RSP-1000-02NM stopped-flow spectrophotometer in MeCN at 298 K, a gradual decrease in the absorption band at 428 nm due to GO was observed, indicating that 2 efficiently scavenged GO. From the time course change in the absorbance at 428 nm, the second-order rate constant (k) for the reaction between 2and GO was determined to be 1.3 × 10 M−1 s−1, which is about 3-fold larger than that of 1 (4.1 M−1 s−1). When Mg(ClO4)2 (0.1−0.3 M) was added to the 2−GO system, no effect of Mg2+ on the k values was observed. Thus, the GO-scavenging reaction by 2 may proceed via the one-step hydrogen-atom transfer rather than the electron transfer followed by proton transfer.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"PACIFICHEM 2021","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ikuo, Nakanishi"}],"nameIdentifiers":[{"nameIdentifier":"1018932","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshimi, Shoji"}],"nameIdentifiers":[{"nameIdentifier":"1018933","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kei, Ohkubo"}],"nameIdentifiers":[{"nameIdentifier":"1018934","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Megumi, Ueno"}],"nameIdentifiers":[{"nameIdentifier":"1018935","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsumoto, Ken-ichiro"}],"nameIdentifiers":[{"nameIdentifier":"1018936","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kiyoshi, Fukuhara"}],"nameIdentifiers":[{"nameIdentifier":"1018937","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroki, Hamada"}],"nameIdentifiers":[{"nameIdentifier":"1018938","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikuo, Nakanishi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1018939","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshimi, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1018940","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kei, Ohkubo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1018941","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Megumi, Ueno","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1018942","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kenichiro, Matsumoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1018943","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Effect of Magnesium Ion on the Radical-Scavenging Reaction of Pterostilbene and the Mechanism","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of Magnesium Ion on the Radical-Scavenging Reaction of Pterostilbene and the Mechanism"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-09"},"publish_date":"2021-12-09","publish_status":"0","recid":"84368","relation_version_is_last":true,"title":["Effect of Magnesium Ion on the Radical-Scavenging Reaction of Pterostilbene and the Mechanism"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T18:28:32.122002+00:00"}