{"created":"2023-05-15T15:02:07.804445+00:00","id":84263,"links":{},"metadata":{"_buckets":{"deposit":"459996d2-7d9b-4089-996f-80a183cd8097"},"_deposit":{"created_by":1,"id":"84263","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"84263"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00084263","sets":["10:28"]},"author_link":["1017878","1017891","1017875","1017882","1017887","1017880","1017879","1017881","1017883","1017876","1017877","1017886","1017892","1017890","1017885","1017884","1017888","1017874","1017889"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2021-05-20","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We measured multi-b-value multi-diffusion-time (MbMTd) DWI and compared ADCs in the ischemic focii of aquaporin4-knockout (AQP4-KO) and wild type (WT) mice. In the ischemic region, AQP4-KO mice showed lower ADCs compared to WT mice, whereas higher ADCs were observed in the contralateral region. In addition, we compared estimates of cell membrane water exchange time obtained by fitting a two-compartment exchange model to the DWI signal. The exchange-time was approximately 2.5 times longer for the AQP4-KO mice than for the WT mice. These results suggest that MbMTd DWI may be useful for in vivo research and clinical diagnosis of AQP4-related diseases.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"ISMRM 2021","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takuya, Urushihata"}],"nameIdentifiers":[{"nameIdentifier":"1017874","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroyuki, Takuwa"}],"nameIdentifiers":[{"nameIdentifier":"1017875","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahashi, Manami"}],"nameIdentifiers":[{"nameIdentifier":"1017876","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasuhiko, Tachibana"}],"nameIdentifiers":[{"nameIdentifier":"1017877","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kershaw, Jeffrey"}],"nameIdentifiers":[{"nameIdentifier":"1017878","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nobuhiro, Nitta"}],"nameIdentifiers":[{"nameIdentifier":"1017879","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sayaka, Shibata"}],"nameIdentifiers":[{"nameIdentifier":"1017880","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasui, Masato"}],"nameIdentifiers":[{"nameIdentifier":"1017881","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Makoto, Higuchi"}],"nameIdentifiers":[{"nameIdentifier":"1017882","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takayuki, Obata"}],"nameIdentifiers":[{"nameIdentifier":"1017883","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takuya, Urushihata","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017884","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroyuki, Takuwa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017885","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahashi, Manami","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017886","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasuhiko, Tachibana","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017887","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kershaw, Jeffrey","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017888","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nobuhiro, Nitta","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017889","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sayaka, Shibata","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017890","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Makoto, Higuchi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017891","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takayuki, Obata","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1017892","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Exploring the effect of aquaporin-4 suppression on cell membrane water exchange in a mouse model of brain ischemia using diffusion-weighted MRI","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Exploring the effect of aquaporin-4 suppression on cell membrane water exchange in a mouse model of brain ischemia using diffusion-weighted MRI"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-17"},"publish_date":"2021-12-17","publish_status":"0","recid":"84263","relation_version_is_last":true,"title":["Exploring the effect of aquaporin-4 suppression on cell membrane water exchange in a mouse model of brain ischemia using diffusion-weighted MRI"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T18:32:53.527022+00:00"}