@article{oai:repo.qst.go.jp:00084044,
 author = {Binder, Tim and Kang, Hangyu and Munetaka, Nitta and Schneider, Florian and Taiga, Yamaya and Parodi, Katia and Wiest, Florian and G Thirolf, Peter and Kang, Hangyu and Munetaka, Nitta and Taiga, Yamaya and Parodi, Katia},
 issue = {12},
 journal = {Physics in Medicine and Biology},
 month = {Jun},
 note = {In this study, we propose a staggered three-layer depth-of-interaction (DOI) detector with a 1 mm crystal pitch and 19.8 mm total crystal thickness for a high-resolution and high-sensitivity small animal in-beam PET scanner. A three-layered stacked LYSO scintillation array (0.9 × 0.9 × 6.6 mm3 crystals, 23 × 22 mm2 surface area)read out by a SiPM array (8 × 8 channels, 3 × 3 mm2 active area/channel and 50 μm microcell size)with data acquisition, signal processing and digitization performed using the PETsys Electronics Evaluations kit(based on the TOFPET v2c ASIC) builds a DOI LYSO detector block. The performance of the DOI detector was evaluated in terms of crystal resolvability, energy resolution, and coincidence resolving time (CRT). A comparative performance evaluation of the staggered three-layer LYSO block was conducted with two different SiPM arrays from KETEK and HAMAMATSU. 100% (KETEK) and 99.8% (HAMAMATSU) of the crystals were identified, by using a flood irradiation the front- and back-side. The average energy resolutions for the 1st, 2nd, and 3rd layers were 16.5 (±2.3)%, 20.9(±4.0)%, and 32.7 (±21.0)% (KETEK) and 19.3 (±3.5)%, 21.2 (±4.1)%, and 26.6 (±10.3)% (HAMAMATSU)for the used SiPM arrays. The measured CRTs(FWHM)for the 1st, 2nd, and 3rd layers were 532 (±111) ps, 463 (±108) ps, and 447 (±111) ps (KETEK) and 402 (±46) ps, 392 (±54) ps, and 408 (±196) ps(HAMAMATSU). In conclusion, the performance of the staggered three-layer DOI detector with 1 mm LYSO pitch and 19.8 mm total crystal thickness was fully characterized. The feasibility of a highly performing readout of a high resolution DOI PET detector via SiPM arrays from KETEK and HAMAMATSU employing the PETsys TOFPET v2c ASIC could be demonstrated.},
 title = {Performance evaluation of a staggered three-layer DOI PET detector using a 1 mm LYSO pitch with PETsys TOFPET2 ASIC: comparison of HAMAMATSU and KETEK SiPMs},
 volume = {66},
 year = {2021}
}