{"created":"2023-05-15T15:01:44.740026+00:00","id":83753,"links":{},"metadata":{"_buckets":{"deposit":"d4b6a468-e817-4726-98bb-b974af2d6374"},"_deposit":{"created_by":1,"id":"83753","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"83753"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00083753","sets":["10:29"]},"author_link":["1009546","1009562","1009551","1009545","1009556","1009560","1009547","1009550","1009544","1009542","1009543","1009559","1009563","1009554","1009557","1009561","1009549","1009558","1009555","1009552","1009553","1009548"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2021-11-04","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"膵がんは生存率が低く、有効な診断・治療法の開発が望まれる。我々はこれまでに、1 cm未満の早期膵がん同所移植モデルにおいて、64Cu標識抗EGFR抗体（セツキシマブ）腹腔投与を用いた高分解能開放型PET（OpenPET）ガイド手術により、早期膵がんを的確に検出し切除できることを報告してきた。本発表では、より浸潤の進んだ>1cmの膵がん同所移植モデルを作成しOpenPETガイド手術を実施し、術中残存膵がん切除における本法の有用性を検討した。【方法・結果】ヒト膵がんxPA-1-RFP細胞液をマウス膵臓に移植しモデルを作成した。64Cu-セツキシマブ（7.4 MBq）を腹腔投与し24h後リアルタイムOpenPETガイド手術を行った。本法より肉眼では検出できない約3mmの膵臓内微小残存膵がんを術中で明瞭に検出し摘出できた。また、OpenPETガイド手術は従来の肉眼による手術に比べ、生存を有意に延長した。【結論】本法は、腫瘍の術中残存を防ぎ、膵がんの生存率改善に寄与すると期待される。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第61回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"吉井, 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