@misc{oai:repo.qst.go.jp:00083626, author = {Kang, Hangyu and Kang, Hangyu}, month = {Oct}, note = {Positron emission tomography (PET) is one of the powerful in vivo molecular imaging devices to explore the functional and biological mechanisms of rodent models. In particular, the mouse brain PET imaging has been playing an important role for the translational research of Alzheimer diseases. For small animal PET, spatial resolution is one of the important parameters to provide the information of radiopharmaceuticals distributions inside mouse brain with high quantification accuracy. Moreover, the depth-of-interaction (DOI) information is essential to minimize the parallax error so as to preserve the spatial resolution at the periphery of the field-of-view. Here we present the design of a small animal DOI PET scanner with GATE to achieve submillimeter resolution. The proposed small animal PET scanner has 53 mm inner diameter and 11 mm axial FOV. The GATE simulation results show a good agreement with those of experimental results in terms of spatial resolution and sensitivity. In conclusion, GATE can be used for the design of a high-resolution small animal DOI PET scanner., 2021 Virtual IEEE Nuclear Science Symposium and Medical Imaging Conference}, title = {Design of a small animal DOI PET scanner using GATE}, year = {2021} }