@article{oai:repo.qst.go.jp:00083024, author = {Takashi, Kaneko and Hiroaki, Suefuji and Masashi, Koto and DEMIZU, YUSUKE and JUN-ICHI, SAITOH and Hiroshi, Tsuji and Tomoaki, Okimoto and Tatsuya, Ohno and Yoshiyuki, Shioyama and Kenji, Nemoto and Takashi, Nakano and Tadashi, Kamada and Takashi, Kaneko and Hiroaki, Suefuji and Masashi, Koto and Hiroshi, Tsuji and Tomoaki, Okimoto and Tatsuya, Ohno and Yoshiyuki, Shioyama and Kenji, Nemoto and Takashi, Nakano and Tadashi, Kamada}, issue = {4}, journal = {in vivo}, month = {Jun}, note = {Abstract. Background/Aim: To evaluate treatment outcomes of carbon-ion radiotherapy for oropharyngeal non-squamous cell carcinoma at four carbon-ion facilities in Japan. Patients and Methods: We retrospectively analyzed the cases of 33 patients with oropharyngeal non-squamous cell carcinoma who were treated with carbon-ion radiotherapy between November 2003 and December 2014. Results: The histology included adenoid cystic carcinoma (n=25) and mucosal malignant melanoma (n=4). No patients had T1 tumors; 23 had T4 tumors. The most-commonly prescribed dose was 57.6 Gy (RBE) in 16 fractions. The median follow-up period was 34.8 months (range=4.2-122.8 months). The 3-year local control and overall survival rates were 94.7% and 90.7%, respectively. There were no grade ≥4 acute adverse events. Only one patient experienced a grade ≥4 late adverse event. No patients experienced late adverse events related to swallowing or salivary function. Conclusion: Carbon-ion radiotherapy appears to be a promising treatment option for oropharyngeal non-squamous cell carcinoma.}, pages = {2239--2245}, title = {Multicenter Study of Carbon-ion Radiotherapy for Oropharyngeal Non-squamous Cell Carcinoma}, volume = {35}, year = {2021} }