{"created":"2023-05-15T15:01:10.463502+00:00","id":82989,"links":{},"metadata":{"_buckets":{"deposit":"5d834160-b2a3-402a-a7ce-21ce84e4d78f"},"_deposit":{"created_by":1,"id":"82989","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"82989"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00082989","sets":["1"]},"author_link":["1015855","1015859","1015852","1015842","1015841","1015860","1015847","1015845","1015851","1015858","1015848","1015846","1015861","1015854","1015853","1015856","1015857","1015850","1015843","1015844","1015849"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"11509","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Scientific reports"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The differentiation of non-small cell lung cancer (NSCLC) and radiation pneumonitis (RP) is critically essential for selecting optimal clinical therapeutic strategies to manage post carbon-ion radiotherapy (CIRT) in patients with NSCLC. The aim of this study was to assess the ability of F-FDG PET/CT metabolic parameters and its textural image features to differentiate NSCLC from RP after CIRT to develop a differential diagnosis of malignancy and benign lesion. We retrospectively analyzed F-FDG PET/CT image data from 32 patients with histopathologically proven NSCLC who were scheduled to undergo CIRT and 31 patients diagnosed with RP after CIRT. The SUV parameters, metabolic tumor volume (MTV), total lesion glycolysis (TLG) as well as fifty-six texture parameters derived from seven matrices were determined using PETSTAT image-analysis software. Data were statistically compared between NSCLC and RP using Wilcoxon rank-sum tests. Diagnostic accuracy was assessed using receiver operating characteristics (ROC) curves. Several texture parameters significantly differed between NSCLC and RP (p < 0.05). The parameters that were high in areas under the ROC curves (AUC) were as follows: SUV, 0.64; GLRLM run percentage, 0.83 and NGTDM coarseness, 0.82. Diagnostic accuracy was improved using GLRLM run percentage or NGTDM coarseness compared with SUV (p < 0.01). The texture parameters of F-FDG uptake yielded excellent outcomes for differentiating NSCLC from radiation pneumonitis after CIRT, which outperformed SUV-based evaluation. In particular, GLRLM run percentage and NGTDM coarseness of F-FDG PET/CT images would be appropriate parameters that can offer high diagnostic accuracy.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nature Publishing Group"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"34075072","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1038/s41598-021-90674-w","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.nature.com/articles/s41598-021-90674-w","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2045-2322","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Suga, Makito"}],"nameIdentifiers":[{"nameIdentifier":"1015841","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishii, Ryuichi"}],"nameIdentifiers":[{"nameIdentifier":"1015842","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miwa, kenta"}],"nameIdentifiers":[{"nameIdentifier":"1015843","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamitaka, Yuto"}],"nameIdentifiers":[{"nameIdentifier":"1015844","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamazaki, Kana"}],"nameIdentifiers":[{"nameIdentifier":"1015845","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tamura, Kentaro"}],"nameIdentifiers":[{"nameIdentifier":"1015846","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Naoyoshi"}],"nameIdentifiers":[{"nameIdentifier":"1015847","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kohno, Ryosuke"}],"nameIdentifiers":[{"nameIdentifier":"1015848","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Masato"}],"nameIdentifiers":[{"nameIdentifier":"1015849","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanimoto, Katsuyuki"}],"nameIdentifiers":[{"nameIdentifier":"1015850","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"1015851","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Higashi, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"1015852","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ryuichi, Nishii","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015853","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yuto, Kamitaka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015854","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kana, Yamazaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015855","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kentaro, Tamura","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015856","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naoyoshi, Yamamoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015857","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ryosuke, Kohno","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015858","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Katsuyuki, Tanimoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015859","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroshi, Tsuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015860","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuya, Higashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1015861","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Differentiation between non-small cell lung cancer and radiation pneumonitis after carbon-ion radiotherapy by 18F-FDG PET/CT texture analysis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Differentiation between non-small cell lung cancer and radiation pneumonitis after carbon-ion radiotherapy by 18F-FDG PET/CT texture analysis"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-06-17"},"publish_date":"2021-06-17","publish_status":"0","recid":"82989","relation_version_is_last":true,"title":["Differentiation between non-small cell lung cancer and radiation pneumonitis after carbon-ion radiotherapy by 18F-FDG PET/CT texture analysis"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T18:42:08.848028+00:00"}