{"created":"2023-05-15T15:00:45.606799+00:00","id":82428,"links":{},"metadata":{"_buckets":{"deposit":"a61c5874-43bb-4cc2-9487-2b86160d955a"},"_deposit":{"created_by":1,"id":"82428","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"82428"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00082428","sets":["11"]},"author_link":["939392","939393","939388","939391","939389","939390","939394","939387"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Nanomaterials (Basel, Switzerland)"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"従来の放射線治療では様々な波長を含んだ白色X線が使用されるが、単色X線は単一のエネルギー準位を持っている。金、銀、ガドリニウムなどの高Z元素に、シンクロトロンで生成された単色X線を、K吸収端以上のエネルギーで照射すると、細胞殺傷につながるDNA損傷を誘発するオージェ電子の放出を含む、光電効果が発生する。ナノ粒子を使用することにより、がん細胞およびがん腫瘍への高Z元素の伝達を促進することができる。高Z元素を含む様々な種類のナノ粒子が開発されている。この増え続けるナノ粒子のリストに最近追加されたのは、ガドリニウムを含むメソポーラスシリカベースのナノ粒子（Gd-MSN）である。腫瘍の成長を阻害するGd-MSNの能力は、正確にエネルギー調整された単色X線をスフェロイドに照射した実験によって実証された。","subitem_description_type":"Abstract"}]},"item_10004_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI AG"}]},"item_10004_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.mdpi.com/2079-4991/10/7/1341","subitem_relation_type_select":"URI"}}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2079-4991","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fuyuhiko, Tamanoi"}],"nameIdentifiers":[{"nameIdentifier":"939387","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsumoto, Kotaro"}],"nameIdentifiers":[{"nameIdentifier":"939388","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Le Hoang Doan, Tan"}],"nameIdentifiers":[{"nameIdentifier":"939389","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ayumi, Shiro"}],"nameIdentifiers":[{"nameIdentifier":"939390","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroyuki, Saito"}],"nameIdentifiers":[{"nameIdentifier":"939391","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fuyuhiko, Tamanoi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"939392","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ayumi, Shiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"939393","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroyuki, Saito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"939394","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-03-23"},"publish_date":"2021-03-23","publish_status":"0","recid":"82428","relation_version_is_last":true,"title":["Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:25:40.401541+00:00"}