{"created":"2023-05-15T15:00:16.595594+00:00","id":81804,"links":{},"metadata":{"_buckets":{"deposit":"d0977809-25b7-40d1-be09-18e94ba6d9bd"},"_deposit":{"created_by":1,"id":"81804","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"81804"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00081804","sets":["11"]},"author_link":["923779","923780"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-02","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"30","bibliographicPageStart":"28","bibliographicVolumeNumber":"225","bibliographic_titles":[{"bibliographic_title":"神経科学ニュース"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"最もポピュラーな化学遺伝学ツール、変異型ムスカリン受容体 DREADDs に作用し、脳移行性・代謝安定性・選択的活性を高いレベルで兼ね備えた新規アゴニスト DCZ を見出しました。副作用が少なく時間精度の高い神経活動操作と行動操作が実現できました。また PET トレーサーとして使うことで、DREADDs 発現部位の高精度の可視化も実現できました。","subitem_description_type":"Abstract"}]},"item_10004_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本神経科学学会"}]},"item_10004_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jnss.org/hp_images/files/fix_page/neuroscience-news/2021/news_211.pdf","subitem_relation_type_select":"URI"}}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"宮川, 尚久"}],"nameIdentifiers":[{"nameIdentifier":"923779","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naohisa, Miyakawa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"923780","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"新規DREADDs アゴニストDCZ の開発と評価 （宮川 尚久）","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新規DREADDs アゴニストDCZ の開発と評価 （宮川 尚久）"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-02-09"},"publish_date":"2021-02-09","publish_status":"0","recid":"81804","relation_version_is_last":true,"title":["新規DREADDs アゴニストDCZ の開発と評価 （宮川 尚久）"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:48:48.600523+00:00"}