@article{oai:repo.qst.go.jp:00081788,
 author = {UKON, YUICHIRO and OUTANI, HIDETATSU and NAGATA, SHIGENORI and KONISHI, EIICHI and Reiko, Imai and DEMIZU, YUSUKE and Tomoaki, Okimoto and NAKA, NORIFUMI and Nobuhito, Araki and Reiko, Imai and Tomoaki, Okimoto and Nobuhito, Araki},
 issue = {5},
 journal = {MOLECULAR AND CLINICAL ONCOLOGY},
 month = {May},
 note = {Chordoma is a rare tumor that originates from the notochord. Half of chordomas involve the sacral region. Surgery is considered to be the standard treatment for sacral chordoma. However, carbon ion radiotherapy (CIRT) has recently emerged as a promising treatment for unresectable sacral chordoma. Little is known about the long-term complications of CIRT. We present two cases of rectotumoral fistula formation that occurred >5 years after CIRT for sacral chordoma. We considered two possible explanations for fistula formation: radiation enterocolitis after CIRT might cause formation of the fistula long-term, and tumor regrowth might compress the rectum and cause fistula formation. A biopsy in Case 1 showed that regrowth tumor was post-CIRT. It is important to be aware of the possibility of rectal complications after CIRT, and if found, resection of the rectum should be considered. This is a first report of rectotumoral fistula formation that occurred >5 years after CIRT for sacral chordoma.},
 pages = {487--491},
 title = {Rectotumoral fistula formation occurring more than 5 years after carbon ion radiotherapy for sacral chordoma: A case report},
 volume = {10},
 year = {2019}
}