{"created":"2023-05-15T15:00:15.843234+00:00","id":81785,"links":{},"metadata":{"_buckets":{"deposit":"ba34e732-0370-4c55-ae06-da34beac3b23"},"_deposit":{"created_by":1,"id":"81785","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"81785"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00081785","sets":["1"]},"author_link":["1006172","1006156","1006157","1006174","1006173","1006170","1006177","1006166","1006171","1006160","1006165","1006168","1006161","1006164","1006163","1006176","1006178","1006169","1006162","1006175","1006158","1006159","1006167"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-09","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographicVolumeNumber":"154","bibliographic_titles":[{"bibliographic_title":"Radiotherapy and oncology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background and purpose: Usefulness of carbon ion radiotherapy (CIRT) for sacral chordoma has been reported from single institutions. We conducted a retrospective nationwide multicentre study to evaluate the clinical outcomes of CIRT for sacral chordoma in Japan. \nMaterials and methods: A total of 219 patients who underwent CIRT for sacral chordoma at institutions across Japan between December 2003 and July 2014 were included in this study. \nResults: Median patient age was 67 years (range, 26-87 years). Most patients had no history of surgical resection (96%). The most frequent planning target volume (PTV) range was 100-500 mL (65%). The most frequently used dose-fractionation was 67.2 Gy (relative biological effectiveness) in 16 fractions (65%). The median follow-up was 56 months (range, 7-132 months). The 5-year overall survival (OS), progression-free survival, and local control rates were 84%, 48%, and 72%, respectively. Frequent sites of out-of-field recurrence included bone (9%) and lung (9%) metastases. The Cox proportional hazards model revealed that both younger age (P = 0.004) and smaller PTV (P = 0.001) were associated with significantly better OS. Acute toxicities of ≥Grade 3 occurred in eight patients (4%). Late toxicities of ≥Grade 3 occurred in 13 patients (6%): skin disorders in six patients (3%), pain in three (1%), myositis in three (1%), etc. CONCLUSION: Our retrospective nationwide multicentre study showed that CIRT for sacral chordoma was effective and safe, and replicated the previously reported data from a representative CIRT institution in Japan demonstrating high local control and low toxicity rates. ","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier "}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"32941958","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.radonc.2020.09.018","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.radonc.2020.09.018","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0167-8140","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Demizu, Yusuke"}],"nameIdentifiers":[{"nameIdentifier":"1006156","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Reiko, Imai"}],"nameIdentifiers":[{"nameIdentifier":"1006157","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroki, Kiyohara"}],"nameIdentifiers":[{"nameIdentifier":"1006158","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akira, Matsunobu"}],"nameIdentifiers":[{"nameIdentifier":"1006159","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masahiko, Okamoto"}],"nameIdentifiers":[{"nameIdentifier":"1006160","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomoaki, Okimoto"}],"nameIdentifiers":[{"nameIdentifier":"1006161","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroshi, Tsuji"}],"nameIdentifiers":[{"nameIdentifier":"1006162","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuya, Ohno"}],"nameIdentifiers":[{"nameIdentifier":"1006163","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshiyuki, Shioyama"}],"nameIdentifiers":[{"nameIdentifier":"1006164","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kenji, Nemoto"}],"nameIdentifiers":[{"nameIdentifier":"1006165","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takashi, Nakano"}],"nameIdentifiers":[{"nameIdentifier":"1006166","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tadashi, Kamada"}],"nameIdentifiers":[{"nameIdentifier":"1006167","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Reiko, Imai","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006168","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroki, Kiyohara","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006169","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akira, Matsunobu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006170","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masahiko, Okamoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006171","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomoaki, Okimoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006172","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroshi, Tsuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006173","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuya, Ohno","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006174","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshiyuki, Shioyama","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006175","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kenji, Nemoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006176","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takashi, Nakano","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006177","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tadashi, Kamada","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1006178","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Carbon ion radiotherapy for sacral chordoma: A retrospective nationwide multicentre study in Japan ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Carbon ion radiotherapy for sacral chordoma: A retrospective nationwide multicentre study in Japan "}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-02-05"},"publish_date":"2021-02-05","publish_status":"0","recid":"81785","relation_version_is_last":true,"title":["Carbon ion radiotherapy for sacral chordoma: A retrospective nationwide multicentre study in Japan "],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:21:14.889796+00:00"}