{"created":"2023-05-15T14:59:48.253961+00:00","id":81150,"links":{},"metadata":{"_buckets":{"deposit":"418cfbce-4ef6-4b4b-aae2-6b73f9729455"},"_deposit":{"created_by":1,"id":"81150","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"81150"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00081150","sets":["1"]},"author_link":["1010920","1010917","1010918","1010916","1010919"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-11","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"1192","bibliographicPageStart":"1185","bibliographicVolumeNumber":"413","bibliographic_titles":[{"bibliographic_title":"Analytical and Bioanalytical Chemistry"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"DNA lesion induced by ionizing radiation and chemicals can cause mutation and carcinogenesis. In particular, clustered DNA damage site (cluster), that is a DNA region with multiple lesions within a few helical turns, is believed to hardly be repaired. However, little is known about the structural details of a cluster. We develop a method to characterize a cluster by fluorescence anisotropy measurements based on Förster resonance energy transfer (FRET) using an irradiated plasmid DNA sample labeled with fluorescent dyes on the lesions. We find that proximity of the lesions and/or probability of cluster formation increase with increasing linear energy transfer (LET) of radiation.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s00216-020-03082-w","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://link.springer.com/article/10.1007/s00216-020-03082-w","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1618-2642","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Akamatsu, Ken"}],"nameIdentifiers":[{"nameIdentifier":"1010916","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shikazono, Naoya"}],"nameIdentifiers":[{"nameIdentifier":"1010917","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saito, Takeshi"}],"nameIdentifiers":[{"nameIdentifier":"1010918","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ken, Akamatsu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1010919","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naoya, Shikazono","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1010920","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Fluorescence anisotropy study of radiation-induced DNA damage clustering based on FRET","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Fluorescence anisotropy study of radiation-induced DNA damage clustering based on FRET"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-08-18"},"publish_date":"2020-08-18","publish_status":"0","recid":"81150","relation_version_is_last":true,"title":["Fluorescence anisotropy study of radiation-induced DNA damage clustering based on FRET"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:02:03.456514+00:00"}