@article{oai:repo.qst.go.jp:00081139, author = {Tashima, Hideaki and Yoshida, Eiji and Iwao, Yuma and Wakizaka, Hidekatsu and Mohammadi, Akram and Nitta, Munetaka and Kitagawa, Atsushi and Inaniwa, Taku and Nishikido, Fumihiko and Tsuji, Atsushi and Nagai, Yuji and Seki, Chie and Minamimoto, Takafumi and Fujibayashi, Yasuhisa and Yamaya, Taiga and Hideaki, Tashima and Eiji, Yoshida and Yuma, Iwao and Hidekatsu, Wakizaka and Mohammadi, Akram and Munetaka, Nitta and Atsushi, Kitagawa and Taku, Inaniwa and Fumihiko, Nishikido and Atsushi, Tsuji and Yuji, Nagai and Chie, Seki and Takafumi, Minamimoto and Yasuhisa, Fujibayashi and Taiga, Yamaya}, issue = {4}, journal = {IEEE Transactions on Radiation and Plasma Medical Sciences}, month = {Nov}, note = {We developed a human-scale single-ring OpenPET (SROP) system, which had an open space allowing us access to the subject during measurement. The SROP system consisted of 160 4-layer depth-of-interaction detectors. The open space with the axial width of 430 mm was achieved with the ring axial width of 214 mm and the ring inner diameter of 660 mm. The detectors were axially shifted to each other so that the detector ring was aligned along a plane horizontally tilted by 45∘ against the axial direction. The system was developed as a mobile scanner to be used not only in clinical PET rooms but also in charged-particle therapy treatment rooms as well as animal experiment rooms. Almost uniform spatial resolution better than 3 mm throughout the entire FOV was realized with an iterative image reconstruction method. Peak absolute sensitivity was 3.1%, and there was a region with sensitivity better than 0.8% for a length of more than 700 mm. An in-beam imaging experiment conducted at the HIMAC showed that the system was operable even at the highest beam intensity available for heavy-ion therapy. In addition, we conducted entire-body monkey dynamic imaging utilizing the long region inside the gantry by positioning a monkey along the direction having the longest FOV tilted by 45∘ against the axial direction. We concluded the developed system realizes versatile PET applications because of its wide-open space and mobility as well as high spatial resolution with sufficiently good sensitivity.}, title = {Development of a multi-use human-scale single-ring OpenPET system}, volume = {61}, year = {2020} }