@inproceedings{oai:repo.qst.go.jp:00080905,
 author = {Seki, Tomohiro and Yamamoto, Kazutoshi and Oshima, Nobu and Itoda, Marino and Kondo, Yohei and Saito, Yutaro and Takakusagi, Yoichi and Kishimoto, Shun and Brender, Jeffery and Malinowski, Ronja and Jan, Henrik Ardenkjær-Larsen and Nonaka, Hiroshi and C Krishna, Murali and Sando, Shinsuke and Yoichi, Takakusagi},
 book = {Proceedings of ISMRM 2020},
 month = {Nov},
 note = {It is well known that dysregulation of γ-glutamyl transferase (GGT) activities in malignant cells lead to more aggressive phenotypes by producing reactive
oxygen species. GGT is important for glutathione homeostasis, and has also been used as a diagnostic marker for various pathologies in the liver, biliary system, and pancreas. Here, for the first time, a novel hyperpolarized 13C probe, γ-Glu-[1-13C]Gly, was demonstrated in vivo tumor xenografts, including human pancreatic ductal adenocarcinoma and ovarian adenocarcinoma, to detect real-time γ-glutamyl transferase activities as a prospective biomarker for monitoring the tumor progression and prognosis with/without various cancer therapeutic approaches.},
 publisher = {ISMRM},
 title = {Novel Real-time Hyperpolarized 13C Metabolic Tracer Probes γ-Glutamyl Transferase Activities in vivo Tumor Xenografts},
 year = {2020}
}