{"created":"2023-05-15T14:59:35.874162+00:00","id":80864,"links":{},"metadata":{"_buckets":{"deposit":"37ed3a8d-2cf5-415b-9bee-2e30f82d67da"},"_deposit":{"created_by":1,"id":"80864","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"80864"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00080864","sets":["10:29"]},"author_link":["916867","916868"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-11-05","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The spatial resolution of a small animal positron emission tomography (PET) scanner deteriorates significantly at the field of view (FOV) periphery due to the parallax error. In a previous study, we proposed a staggered 3-layer depth-of-interaction (DOI) detector with a 1 mm crystal pitch to achieve high resolution while minimizing the parallax error. In this study, we present the initial results of a prototype small animal PET scanner using a staggered 3-layer DOI detector for submillimeter mouse brain imaging. The prototype small animal PET scanner had a 52 mm inner diameter and 11 mm axial coverage. The LYSO crystal array had the pixel pitch of 1 mm and total thickness of 15 mm. The PET scanner consisted of 16 DOI detectors which of each had a 3-layer staggered LYSO crystal array. The LYSO crystal array was optically coupled to a 4×4 SiPM (Hamamatsu, S14161-3050HS-04, Japan) array with a pixel pitch of 3.2 mm. The SiPM anode signals were multiplexed using a resistive network and then digitized by the Hamamatsu DAQ with an integration time of 250 ns. The coincidence data were generated by using coincidence process software with a coincidence window of 20 ns. The measured spatial resolutions at the center and 15 mm radial offset were 0.67 mm, and 1.56 mm for filtered-back-projection (FBP), and 0.50 mm, and 1.16 mm for ordered-subset-expectation-maximization (OSEM), respectively. The peak absolute sensitivity was 0.76% with an energy window of 400-600 keV. In conclusion, we developed a high-resolution and high-sensitivity mouse brain dedicated PET scanner with 3-layer DOI detectors. In the near future, we will perform a mouse brain imaging study using the prototype PET scanner.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"2020 Virtual IEEE Nuclear Science Symposium and Medical Imaging Conference","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kang, Hangyu"}],"nameIdentifiers":[{"nameIdentifier":"916867","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kang, Hangyu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"916868","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Initial Imaging Results of a Mouse Brain PET Prototype with a Staggered 3-Layer DOI Detector","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Initial Imaging Results of a Mouse Brain PET Prototype with a Staggered 3-Layer DOI Detector"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-11-02"},"publish_date":"2020-11-02","publish_status":"0","recid":"80864","relation_version_is_last":true,"title":["Initial Imaging Results of a Mouse Brain PET Prototype with a Staggered 3-Layer DOI Detector"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:56:52.895231+00:00"}