{"created":"2023-05-15T14:59:32.449567+00:00","id":80788,"links":{},"metadata":{"_buckets":{"deposit":"cf42df28-dfd1-4136-973e-79ad2fc9886a"},"_deposit":{"created_by":1,"id":"80788","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"80788"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00080788","sets":["10:28"]},"author_link":["895507","895508","895510","895503","895506","895509","895511","895504","895505","895502"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-11-13","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Vascular endothelial growth factor receptors (VEGFRs) are well recognized as  significant biomarkers of tumor angiogenesis. Herein, we have developed a f\nirst－of－its-kind peptide－based VEGFR positron emission tomography (PET) t racer. The novel [64Cu]VEGF125－136 peptide possessed satisfactory radio－ch\naracteristics and showed good specificity for the visualization of VEGFR in various mouse models, in which the tumorspecific radioactivity uptake was hi ghly correlated to the VEGFR expression level. Moreover, the tracer showed h igh tumor uptake (ca. 5.89 %ID/g at 20 min postinjection in B16F10 mice) and  excellent pharmacokinetics, achieving the maximum imaging quality within 1 h after injection. These features convey [64Cu]VEGF125－136 as a promising, clinically translatable PET tracer for the imaging of tumor angiogenesis.\n","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第60回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kuan, Hu"}],"nameIdentifiers":[{"nameIdentifier":"895502","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Xie, Lin"}],"nameIdentifiers":[{"nameIdentifier":"895503","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zhang, Yiding"}],"nameIdentifiers":[{"nameIdentifier":"895504","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hanyu, Masayuki"}],"nameIdentifiers":[{"nameIdentifier":"895505","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ming-Rong, Zhang"}],"nameIdentifiers":[{"nameIdentifier":"895506","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kuan, Hu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"895507","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Xie, Lin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"895508","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zhang, Yiding","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"895509","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hanyu, Masayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"895510","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ming-Rong, Zhang","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"895511","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"PET Imaging of VEGFR with a Novel <SUP>64</SUP>Cu Labeled Peptide","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"PET Imaging of VEGFR with a Novel <SUP>64</SUP>Cu Labeled Peptide"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-23"},"publish_date":"2020-10-23","publish_status":"0","recid":"80788","relation_version_is_last":true,"title":["PET Imaging of VEGFR with a Novel <SUP>64</SUP>Cu Labeled Peptide"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:23:55.528471+00:00"}