@inproceedings{oai:repo.qst.go.jp:00080771,
 author = {Shinoto, Hitoshi and Tokuda, Takahiko and Shinoto, Hitoshi and Tokuda, Takahiko},
 book = {Neurology},
 issue = {9},
 month = {Sep},
 note = {This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.








The search for an accurate, reliable, early disease biomarker for Parkinson disease (PD) from an easily accessible source is a high priority.1 α-Synuclein (α-Syn) is a small protein largely present in the CNS at the presynaptic neuronal terminals. The cause of PD is not clear, but aggregation or posttranslational modifications of α-Syn are currently thought to be an essential link in the chain of events leading to PD.1,2 Lewy type α-Syn deposition is found not only in the CNS but also in the peripheral nervous system of multiple organs including the endocrine glands, skin, stomach, and colon in PD with rostral-caudal gradient within the gastrointestinal gract.1,3 α-Syn is normally released by neuronal cells and is present in CSF and plasma.},
 pages = {373--374},
 title = {Systemic Synuclein Sampling Study toward a Parkinson disease biomarker},
 volume = {95},
 year = {2020}
}