{"created":"2023-05-15T14:59:28.062639+00:00","id":80684,"links":{},"metadata":{"_buckets":{"deposit":"5c5a131b-6869-4d4a-ab93-77259e46bcd2"},"_deposit":{"created_by":1,"id":"80684","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"80684"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00080684","sets":["1"]},"author_link":["1013961","1013967","1013962","1013966","1013964","1013963","1013965","1013960"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"5502","bibliographicPageStart":"5497","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"ANTICANCER RESEARCH"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background/aim: The cell-killing and radiosensitizing effects of carbon-ion (C-ion) beams with low linear energy transfer (LET) are underexplored. We aimed to demonstrate the cell-killing effects of 60Co gamma rays and C-ion beams at various LET values and the radiosensitizing effect of C-ion beams at various LET and cisplatin levels. \nMaterials and methods: Human uterine cervical cancer cells were irradiated with 60Co gamma rays and C-ion beams at different levels of LET, with and without cisplatin treatment. \nResults: Low-LET C-ion beams had a superior cell-killing effect compared to 60Co gamma rays. Survival curves under low-LET C-ion beams were more similar to that of 60Co gamma rays than that of high-LET C-ion beams. Cisplatin significantly reduced cell survival after 1, 2, and 3 Gy C-ion beam irradiations at LET values of 13/30/70 keV/μm, 13/30 keV/μm, and 13 keV/μm, respectively. \nConclusion: Low-LET C-ion beams combined with cisplatin have higher radiosensitizing effects than high-LET C-ion beams. ","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":" International Institute of Anticancer Research"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"32988872","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.21873/anticanres.14561","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ar.iiarjournals.org/content/40/10/5497.full","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0250-7005","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shiba, Shintaro"}],"nameIdentifiers":[{"nameIdentifier":"1013960","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wakatsuki, Masaru"}],"nameIdentifiers":[{"nameIdentifier":"1013961","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohno, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"1013962","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakano, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"1013963","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shintaro, Shiba","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1013964","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masaru, Wakatsuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1013965","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuya, Ohno","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1013966","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takashi, Nakano","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1013967","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Differences in Linear Energy Transfer Affect Cell-killing and Radiosensitizing Effects of Spread-out Carbon-ion Beams","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Differences in Linear Energy Transfer Affect Cell-killing and Radiosensitizing Effects of Spread-out Carbon-ion Beams"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-09"},"publish_date":"2020-10-09","publish_status":"0","recid":"80684","relation_version_is_last":true,"title":["Differences in Linear Energy Transfer Affect Cell-killing and Radiosensitizing Effects of Spread-out Carbon-ion Beams"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T18:50:27.019252+00:00"}