@misc{oai:repo.qst.go.jp:00080635,
 author = {鈴木, 雅雄 and Suzuki, Masao},
 month = {Oct},
 note = {The last year we reported the enhancement of cell-killing effect irradiated with carbon ions by applying longitudinal magnetic field. This year we examined the mechanism of the effect, focusing on cellular response(s) via gap-junction mediated cell-cell communication. Normal human skin fibroblasts and cervical epitheloid carcinoma cells were irradiated with carbon ions (350MeV/n, LET~12keV/µm) accelerated with the Heavy Ion Medical Accelerator in Chiba under the longitudinal magnetic field (0.6T) with or without a specific inhibitor of gap junction (40 µM of gamma-isomer of hexachloro-cyclohexane). The cell-killing effects treated with the magnetic field were 1.3 ~ 1.5 times higher than those of carbon ion alone. When using the gap-junction inhibitor, the cell-killing effects were enhanced as the same level among the magnetic field alone, the gap-junction inhibitor alone and both treatments. There is evidence that the enhanced effect by the longitudinal magnetic fields is induced by cellular response(s) via gap-junction mediated cell-cell communication. (This is the co-operative study with Drs.T.Inaniwa, N.Usami, S.Sato, A.Noda, M.Muramatsu, Y.Iwata, N.Kanematsu, T.Shirai, K.Noda), 第79回日本癌学会学術総会},
 title = {The enhancement of cell-killing effect irradiated with carbon-ion beams by applying longitudinal magnetic field relate to cellular response via gap-junction mediated cell-cell communication},
 year = {2020}
}