@article{oai:repo.qst.go.jp:00080209,
 author = {Matsumoto, Yoshitaka and Hattori, Kenjiro and Arima, Hidetoshi and Motoyama, Keiichi and Higashi, Taishi and Ishikawa, Hitoshi and Fukumitsu, Nobuyoshi and Aihara, Teruhito and Nakai, Kei and Kumada, Hiroaki and Sakurai, Hideyuki and Matsumoto, Yoshitaka and Ishikawa, Hitoshi and Nakai, Kei and Sakurai, Hideyuki},
 journal = {Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine},
 month = {Sep},
 note = {In this study, the tumor accumulation and antitumor effect of folate-modified cyclodextrin (ND201) purified with folate receptor (FR) connotated with BSH were examined. ND201 and BSH were stably bound in blood, and the mixing ratio 1:1 was most efficient. ND-BSH showed higher boron concentration (38.5 ppm) than BSH alone (11.25 ppm). The maximum ND-BSH tumor/blood ratio was also markedly higher (6.58) than that of BSH alone (1.04). ND-BSH showed a significant antitumor effect compared with BSH after neutron irradiation.},
 title = {Folate-appended cyclodextrin improves the intratumoral accumulation of existing boron compounds.},
 volume = {163},
 year = {2020}
}