{"created":"2023-05-15T14:58:56.634246+00:00","id":79967,"links":{},"metadata":{"_buckets":{"deposit":"d9815a83-9eba-4eee-a687-0881e2d1a033"},"_deposit":{"created_by":1,"id":"79967","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"79967"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00079967","sets":["1"]},"author_link":["868423","868422","868424","868425"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-05","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"82","bibliographicPageStart":"74","bibliographicVolumeNumber":"74","bibliographic_titles":[{"bibliographic_title":"Physica Medica"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: To evaluate the patients’ set-up error-induced perturbation effects on 4D dose distributions (4DDD) of range-adapted internal target volume-based (raITV) treatment plan using lung and liver 4DCT data sets. Methods: We enrolled 20 patients with lung and liver cancer treated with respiratory-gated carbon-ion beam scanning therapy. PTVs were generated by adding a 2 mm range-adapted set-up margin on the raITVs. Set-up errors were simulated by shifting the beam isocenter in three translational directions of±2 mm,±4 mm, and ± 6 mm. 4DDDs were calculated for both nominal and isocenter-shifted situations. Dose metrics of CTV dose coverage (D95) and normal tissue sparing were evaluated. Statistical significance with p < 0.01 was considered by Wilcoxon signed rank test.\nResults: The CTV dose coverage was more sensitive to set-up errors for lung cases than for liver cases, and more serious in superior-inferior direction. The sufficient CTV-D95 > 98% could be achieved with set-up errors less than ± 2 mm in all shift directions both for lung and liver cases. With the increase of set-up error, the CTV dose coverage decreased gradually. The clinical criterial of CTV-D95 > 95% could not be fulfilled with set-up error reached to ± 4 mm for lung cases, and ± 6 mm for liver cases. OAR doses did not have a significant difference with each set-up error for both lung and liver cases.\nConclusions: The range-adapted set-up margin successfully prevented dose degradation of 4DDDs in the presence of the same magnitude of set-up error for raITV-based carbon-ion beam scanning therapy.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.ejmp.2020.05.003","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.sciencedirect.com/science/article/pii/S1120179720301149","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1120-1797","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"He, Pengbo"}],"nameIdentifiers":[{"nameIdentifier":"868422","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mori, Shinichiro"}],"nameIdentifiers":[{"nameIdentifier":"868423","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"He, Pengbo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"868424","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mori, Shinichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"868425","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Perturbation analysis of 4D dose distribution for scanned carbon-ion beam radiotherapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Perturbation analysis of 4D dose distribution for scanned carbon-ion beam radiotherapy"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-05-20"},"publish_date":"2020-05-20","publish_status":"0","recid":"79967","relation_version_is_last":true,"title":["Perturbation analysis of 4D dose distribution for scanned carbon-ion beam radiotherapy"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:54:57.300879+00:00"}