@article{oai:repo.qst.go.jp:00079914,
 author = {Kuan, Hu and Shang, Jingjie and Xie, Lin and Hanyu, Masayuki and Zhang, Yiding and Yang, Zhimin and Xu, Hao and Lu, Wang and Ming-Rong, Zhang and Kuan, Hu and Lin, Xie and Masayuki, Hanyu and Zhang, Yiding and Yang, Zhimin and Lu, Wang and Zhang, Ming-Rong},
 issue = {5},
 journal = {ACS Omega},
 month = {Apr},
 note = {Vascular endothelial growth factor receptors (VEGFRs) are well recognized as significant biomarkers of tumor angiogenesis. Herein, we have developed a first-of-its-kind peptide-based VEGFR positron emission tomography (PET) tracer. The novel [64Cu]VEGF125–136 peptide possessed satisfactory radio-characteristics and showed good specificity for the visualization of VEGFR in various mouse models, in which the tumor-specific radioactivity uptake was highly correlated to the VEGFR expression level. Moreover, the tracer showed high tumor uptake (ca. 5.89 %ID/g at 20 min postinjection in B16F10 mice) and excellent pharmacokinetics, achieving the maximum imaging quality within 1 h after injection. These features convey [64Cu]VEGF125–136 as a promising, clinically translatable PET tracer for the imaging of tumor angiogenesis.},
 pages = {8508--8514},
 title = {PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide},
 volume = {2020},
 year = {2020}
}