{"created":"2023-05-15T14:58:10.003067+00:00","id":78896,"links":{},"metadata":{"_buckets":{"deposit":"c0dd10f9-e4dc-4115-bf54-96e24830c3d5"},"_deposit":{"created_by":1,"id":"78896","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"78896"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00078896","sets":["1"]},"author_link":["997070","997067","997074","997079","997068","997069","997071","997066","997065","997077","997073","997075","997076","997078","997064","997072"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"109","bibliographicPageStart":"101","bibliographicVolumeNumber":"465","bibliographic_titles":[{"bibliographic_title":"Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms "}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 μm when the distance between the beam exit from vacuum to the irradiation device is less than 500 μm for 13.0 MeV/n 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 μm was obtained for 12C ions of 26.7 MeV/n at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans  for irradiation using the new device are reported, and the results of the first irradiation experiments presented.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.nimb.2019.12.028","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.sciencedirect.com/science/article/pii/S0168583X1930847X","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0168-583X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Funayama, Tomoo"}],"nameIdentifiers":[{"nameIdentifier":"997064","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakashita, Tetsuya"}],"nameIdentifiers":[{"nameIdentifier":"997065","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Michiyo"}],"nameIdentifiers":[{"nameIdentifier":"997066","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yokota, Yuichiro"}],"nameIdentifiers":[{"nameIdentifier":"997067","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miyawaki, Nobumasa"}],"nameIdentifiers":[{"nameIdentifier":"997068","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kashiwagi, Hirotsugu"}],"nameIdentifiers":[{"nameIdentifier":"997069","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoh, Takahiro"}],"nameIdentifiers":[{"nameIdentifier":"997070","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kurashima, Satoshi"}],"nameIdentifiers":[{"nameIdentifier":"997071","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomo, Funayama","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997072","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tetsuya, Sakashita","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997073","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Michiyo, Suzuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997074","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yuuichiro, Yokota","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997075","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nobumasa, Miyawaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997076","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirotsugu, Kashiwagi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997077","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahiro, Satoh","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997078","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoshi, Kurashima","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997079","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-01-07"},"publish_date":"2020-01-07","publish_status":"0","recid":"78896","relation_version_is_last":true,"title":["An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:54:49.505443+00:00"}