{"created":"2023-05-15T14:57:50.698570+00:00","id":78464,"links":{},"metadata":{"_buckets":{"deposit":"79abb498-f795-474d-89ee-75cd5214f8d4"},"_deposit":{"created_by":1,"id":"78464","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"78464"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00078464","sets":["1"]},"author_link":["997857","997855","997860","997856","997858","997859"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"23","bibliographicPageEnd":"7509","bibliographicPageStart":"7505","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Journal of Physical Chemistry Letters"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Characterization of the dynamics of disordered polypeptide chains is required to elucidate the behavior of intrinsically disordered proteins and proteins under non-native states related to the folding process. Here we develop a method using quasielastic neutron scattering, combined with small-angle X-ray scattering and dynamic light scattering, to evaluate segmental motions of proteins as well as diffusion of the entire molecules and local side chain motions. We apply this method to RNase A under the unfolded and molten-globule (MG) states. The diffusion coefficients arising from the segmental motions are evaluated, and found to be different between the unfolded and MG states. The values obtained here are consistent with those obtained using the fluorescence-based techniques. These results demonstrate not only feasibility of this method but also usefulness to characterize the behavior of proteins under various disordered states.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"ACS Publications"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1021/acs.jpclett.9b03196","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubs.acs.org/doi/10.1021/acs.jpclett.9b03196","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1948-7185","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fujiwara, Satoru"}],"nameIdentifiers":[{"nameIdentifier":"997855","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsuo, Tatsuhito"}],"nameIdentifiers":[{"nameIdentifier":"997856","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugimoto, Yasunobu"}],"nameIdentifiers":[{"nameIdentifier":"997857","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shibata, Kaoru"}],"nameIdentifiers":[{"nameIdentifier":"997858","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satoru, Fujiwara","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997859","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsuhito, Matsuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"997860","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Segmental Motions of Proteins under Non-Native States Evaluated Using Quasielastic Neutron Scattering","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Segmental Motions of Proteins under Non-Native States Evaluated Using Quasielastic Neutron Scattering"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-11-20"},"publish_date":"2019-11-20","publish_status":"0","recid":"78464","relation_version_is_last":true,"title":["Segmental Motions of Proteins under Non-Native States Evaluated Using Quasielastic Neutron Scattering"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:51:25.473262+00:00"}